Study of Social Cognition in Adults with Type 1 or Type 2 Narcolepsy Compared to Idiopathic Hypersomnia

What this Trial Is About

This research aims to evaluate social cognition and related cognitive functions in adults diagnosed with type 1 or type 2 narcolepsy or idiopathic hypersomnia. Narcolepsy is a chronic neurological disorder characterized by excessive daytime sleepiness, with type 1 linked to hypocretin deficiency and cataplexy symptoms, and type 2 showing normal hypocretin levels without cataplexy. The study addresses the impact of narcolepsy on social cognition, mood, attention, and decision-making, areas that have not been extensively studied, especially with control groups for comparison. Participants will be randomized into three groups type 1 narcolepsy, type 2 narcolepsy, and idiopathic hypersomnia. Each participant will undergo psychometric evaluation through validated questionnaires assessing social cognition and cognitive functions. The questionnaires include the Sustained Attention to Response Task SART, Iowa Gambling Task IGT, Impulsive Behaviour Scale UPPS, Toronto Alexithymia Scale TAS, Basic Empathy Scale BES, Facial Emotions Recognition Task FRET, ERF-CS, and the Movie for the Assessment of Social Cognition MASC. During the two-year study period, participants will complete these assessments alongside their usual care. Researchers will measure mean scores on the SART, IGT, and UPPS across the three groups to understand cognitive and social cognition differences. The study is triple-masked and randomized, with careful monitoring of participant responses to these questionnaires to explore social and cognitive aspects of these sleep disorders.

Evaluation of Social Cognition in Patient With Type 1 or Type 2 Narcolepsy Versus Patients With Idiopathic Hypersomnia