Actively Recruiting

Phase Not Applicable
Age: 10Years - 20Years
All Genders
Healthy Volunteers
ID05194254

MRI-Eye Tracking Pairing to Assess Social Cognition Development in Children and Young Adults With Autism Spectrum Disorder

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2025-05-28

68

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying social cognition development in children and young adults with Autism Spectrum Disorder (ASD) aged 10 to 20 years. The study aims to improve the assessment of joint attention, a key social skill, by using a new approach that combines functional MRI (fMRI) and eye-tracking to create more realistic visual environments. This method will help explore how perception of joint attention changes over time in autistic individuals compared to typically developing peers. Participants include two groups: those with ASD and a control group with typical development. Both groups undergo MRI and eye-tracking assessments that mimic real social interactions through video-based visual stimuli. This study is non-randomized and observational, focusing on comparing brain and eye movement responses between groups to better understand neurodevelopmental differences. During the study, participants will complete cognitive evaluations, including IQ tests, and undergo MRI and eye-tracking sessions. Researchers will measure differences in brain mapping and eye movements related to joint attention between groups in a single-day assessment. Safety monitoring includes screening for MRI contraindications, and participants must provide informed consent. The total participation time is mainly a single day for these assessments.

CONDITIONS

Brief Title

MRI-Eye Tracking Pairing, a Tool for Assessing Social Cognition in Children With ASD

Who Can Participate

Age: 10Years - 20Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 10 to 20 years old
  • Diagnosis of Autism Spectrum Disorder (CARS score 6) 30 or higher for the ASD group
  • Diagnosis of typical development (CARS score less than 30) for the control group
  • IQ test evaluation performed by a trained psychologist
  • Obtaining informed oral and written consent from participant and legal guardian
  • Affiliated with social security
  • No contraindication to magnetic resonance imaging
Not Eligible

You will not qualify if you...

  • Age outside the range of 10 to 20 years
  • Contraindications to MRI such as claustrophobia, pacemaker, or metal implants
  • Major obesity exceeding 140 kg preventing MRI tunnel entry
  • Pregnancy or breastfeeding
  • Under legal guardianship or deprived of liberty
  • For control group: psychiatric disorders like ADHD, depression, bipolar disorder, schizophrenia
  • For control group: neurological history such as epilepsy or neurovascular accident

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants undergo MRI and Eye Tracking assessments to evaluate social cognition.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

CHU Amiens Picardie

Amiens, Picardie, France, 80054

Actively Recruiting

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Research Team

J

Jean-Marc Constans, Pr

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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