Actively Recruiting
MRI-Eye Tracking Pairing, a Tool for Assessing Social Cognition in Children With ASD
Led by Centre Hospitalier Universitaire, Amiens · Updated on 2025-05-28
68
Participants Needed
1
Research Sites
177 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Most studies use static visual percepts that are less representative of joint attention versus an ecological environment. This has the consequence of decreasing the perception of an interaction with a social partner, which is an essential step in achieving joint attention. The originality of this study is to improve the design of visual percepts (in the form of video) in order to mimic an ecological environment as much as possible by using MRI-ET coupling. The second originality of this study is the longitudinal exploration of the neurodevelopment of social cognition in autistic children. Studies by the Redcay and Oberwelland teams observe different activations at different ages. The hypothesis is that the perception of joint attention varies over time in people with ASD. To date, there are no studies to determine the influence of childhood neurodevelopment in autistic people on the perception of joint attention. It would be unprecedented to use the MRI-ET pairing as a tool for assessing social cognition as a function of the development of children with ASD.
CONDITIONS
Official Title
MRI-Eye Tracking Pairing, a Tool for Assessing Social Cognition in Children With ASD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 10 to 20 years old
- Diagnosis of Autism Spectrum Disorder (ASD) with CARS score 60 performed at inclusion for experimental group
- Diagnosis of ASD with CARS score <30 performed at inclusion for control group
- IQ test evaluation performed by a trained psychologist
- Informed oral and written consent obtained after appropriate information
- Informed oral and written consent from legal guardian obtained after information
- Affiliated with social security
- No contraindication to magnetic resonance imaging
You will not qualify if you...
- Age outside the range of 10 to 20 years
- Contraindications to MRI, including claustrophobia, pacemaker, neurosurgical clips, vascular clips, heart valves, ventriculoperitoneal valves, cochlear implant, neurostimulator, intraocular metal shards, joint prosthesis
- Major obesity (> 140 kg) preventing entry into MRI machine (diameter <70cm)
- Pregnant or breastfeeding women
- Persons under legal guardianship or deprived of liberty by judicial or administrative decision
- For control group: psychiatric disorders such as attention disorder with or without hyperactivity, depression, bipolar disorder, schizophrenia
- For control group: neurological history such as epilepsy or neurovascular accident
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
CHU Amiens Picardie
Amiens, Picardie, France, 80054
Actively Recruiting
Research Team
J
Jean-Marc Constans, Pr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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