Actively Recruiting
Evaluation of the Stability of Sulfur Volatile Compounds From Exhaled Air for Halitosis Diagnosis
Led by University Hospital, Strasbourg, France · Updated on 2025-08-06
100
Participants Needed
1
Research Sites
47 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Halitosis or bad breath is a problem affecting 30% of the world's population. There are many causes, and oral pathologies, including periodontitis, are the main etiology. In order to make a diagnosis, a clinical interview is necessary to distinguish true halitosis from psychological halitosis. In addition, a measurement of volatile sulfur compounds (VSC), the main molecules involved in bad breath, is necessary. This is done during the consultation by measuring the concentration of VSCs in exhaled air. However, few private practices or hospitals have the necessary equipment to measure VSC. As a result, patients are often obliged to travel long distances to obtain a consultation including this specific VSC analysis. The aim of this study is to evaluate the stability of VSC values obtained in gaseous samples up to 7 days after sampling, in order to assess the clinical relevance of analyzing samples at a distance from sampling. The clinical aim is to determine whether self-sampling by the patient at home and extemporaneous analysis could be considered in the diagnosis of halitosis.
CONDITIONS
Official Title
Evaluation of the Stability of Sulfur Volatile Compounds From Exhaled Air for Halitosis Diagnosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult, male or female
- Affiliated with a social health insurance plan
- Able to understand the study's objectives and risks and provide dated and signed informed consent
- Presenting for consultation for diagnosis and treatment of periodontal disease
You will not qualify if you...
- Under safeguard of justice
- Under guardianship or curatorship
- Pregnant or breastfeeding
- Unable to receive informed information (emergency situation, comprehension difficulties, etc.)
- Currently enrolled in another clinical research study or in an exclusion period
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Clinique dentaire
Strasbourg, France, 67000
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
0
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