Actively Recruiting
Role of Kefir Mouth Wash in Oral Health Status Amelioration
Led by Al-Mustansiriyah University · Updated on 2025-04-24
60
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The present research aims to evaluate the efficiency of kefir mouthwash in enhancing oral health status by employing an in vivo experimental approach. Specifically, the study will assess how kefir mouthwash influences key oral health indicators, including gingival inflammation, plaque development, oral hygiene status, and halitosis. The study will be conducted over a 28-day period, with follow-up assessments every 14 days. The study will include systemically healthy adults with moderate gingivitis. Clinical parameters such as the Gingival Index (GI), Plaque Index (PI), and Simplified Oral Hygiene Index (OHI-S) will be measured, along with inflammatory biomarkers, including Interleukin-1β (IL-1β) and Interleukin-10 (IL-10). Halitosis will be evaluated using a Hali meter device. All of these will be measured at base line and day 14 and day 28 end of the study. Chlorhexidine 0.12% will be used as a comparative control to evaluate the efficacy of kefir mouthwash in improving oral health. This research intends to provide scientific evidence supporting the use of kefir as a probiotic-based mouthwash, offering a natural alternative to chemical mouthwashes and potentially reducing the negative consequences commonly associated with their use.
CONDITIONS
Official Title
Role of Kefir Mouth Wash in Oral Health Status Amelioration
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age range 18-28 years.
- Systemically healthy people without a history of chronic illness.
- Those suffering with moderate gingivitis.
- Not using any antibiotics over three months
You will not qualify if you...
- History of systemic diseases.
- Pregnant, lactating females.
- History of antibiotic therapy in the past 3 months.
- History of oral prophylaxis within the last 6 months prior to the study.
- Subjects with mouth breathing habits.
- Subjects with orthodontic and prosthodontic appliances.
- Subjects with deleterious habits such as smoking.
- Failure to follow the prescription regimen.
- Failure to follow the research protocol.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Al-Mustansiriyah University/College of Dentistry
Baghdad, Iraq
Actively Recruiting
Research Team
Z
Zahra H Al-Tamimi, MS student
CONTACT
Z
Zahra H Al-Tamimi, MS student
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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