Actively Recruiting
Exercise Effects on Adipose Tissue Structure and Function
Led by University of Michigan · Updated on 2025-06-29
46
Participants Needed
1
Research Sites
469 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Participants will be randomized into one of two different experimental groups: 1) Exercise group and 2) No exercise (control group). Subject participation in the study will involve a series of metabolic tests before and after participants undergo a 10% weight loss program (with or without exercise training depending on group randomization). After completing this weight loss portion of the study, participants will then be required to adhere to a high calorie diet program to regain half of the weight the participant lost - followed by the same series of metabolic tests.
CONDITIONS
Official Title
Exercise Effects on Adipose Tissue Structure and Function
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age: 18-40 years
- Body Mass Index: 27-45 kg/m2
- No regularly planned exercise or physical activity for at least 6 months
- Women must have regular menstrual cycles and be premenopausal
You will not qualify if you...
- History or evidence of cardiovascular or metabolic disease
- Use of medications that affect lipid or glucose metabolism or inflammation
- Weight changes of 6 pounds or more in the last 3 months
- Current tobacco or e-cigarette use
- Women who are pregnant or actively breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Michigan
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
Research Team
S
Suzette Howton
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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