Actively Recruiting
Exercise Magnetic Resonance Imaging in Patients With Obesity Associated Heart Failure
Led by University Medical Center Groningen · Updated on 2024-07-23
50
Participants Needed
1
Research Sites
102 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To aim of the EXPOSURE study is to investigate the effects of epicardial fat on cardiac function, pericardial constraint and pulmonary artery vasodilatation using cardiac magnetic resonance (CMR) imaging at rest and during exercise stress testing in patients with HFpEF.
CONDITIONS
Official Title
Exercise Magnetic Resonance Imaging in Patients With Obesity Associated Heart Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signs and symptoms of heart failure according to the European Society of Cardiology guideline
- Left ventricular ejection fraction 40% or higher
- HFA-PEFF score of 5 or higher, or score 2-4 with a positive stress test
- Age over 18 years
- In sinus rhythm
- Able to perform a bicycle exercise test
- Willing to sign informed consent
You will not qualify if you...
- Body weight over 140 kg
- Atrial fibrillation or other significant arrhythmia during assessment
- Contraindications for cardiac magnetic resonance imaging (e.g., claustrophobia, implanted cardiac devices)
- Myocardial infarction, percutaneous coronary intervention, or coronary artery bypass graft within 3 months, or untreated severe obstructive coronary artery stenosis
- More than moderate left-sided valve disease
- Complex congenital heart disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Medical Center Groningen
Groningen, Netherlands, 9713GZ
Actively Recruiting
Research Team
T
Thomas M Gorter, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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