Actively Recruiting
Families Left Behind
Led by RAND · Updated on 2025-08-21
340
Participants Needed
4
Research Sites
276 weeks
Total Duration
On this page
Sponsors
R
RAND
Lead Sponsor
S
Stanford University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The United States is facing unprecedented rates of drug overdose deaths, profoundly impacting millions of families who are left to navigate their grief. Those bereaved by overdose experience a unique form of grief characterized by feelings of guilt, shame, and blame, which can worsen their suffering and deter them from seeking help. Individuals coping with overdose loss often endure more severe health consequences compared to those grieving non-drug related deaths, including prolonged grief disorder, substance use disorders, PTSD, depression, and suicidal thoughts. Moreover, bereaved individuals, particularly those with a history of substance use, may engage in risky behaviors as a means of coping, further exacerbating the risk of overdose and mortality within this vulnerable population. Peer grief support interventions have emerged as a promising approach to assist those experiencing such losses. To combat these outcomes, we are collaborating with Peer Community Support Partners (PSCP) in a novel practice-research partnership to implement the RIVER peer grief support model. Though RIVER has shown success in community settings, it has yet to be rigorously evaluated. In a three-aim approach, this study aims to assess the effectiveness of the RIVER model while also enhancing and engaging grievers with support resources via medical examiner offices (MEOs), which routinely contact families during death investigations. This research represents a pivotal advancement in addressing the needs of the overlooked bereaved community, aligning with the NIH's Helping to End Addiction Long-term (HEAL) initiative to develop effective strategies against the opioid crisis. Together, community engagement and rigorous research efforts aim to enhance support for those affected by the tragedy of drug overdose.
CONDITIONS
Official Title
Families Left Behind
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Lost a loved one to an unintentional drug overdose within the past year
- Age 18 years or older
- Fluent in English or Spanish
- Able to give consent (no severe cognitive impairment, active psychosis, or developmental disabilities)
You will not qualify if you...
- Need hospitalization for psychiatric symptoms or substance use disorders
- Active suicidal ideation
- Lost someone to drug overdose more than one year ago
- Lost someone to a drug overdose death that was suicidal or of undetermined intent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Jefferson County Coroner/Medical Examiner's Office
Birmingham, Alabama, United States, 35203
Actively Recruiting
2
San Diego County Medical Examiner Office
San Diego, California, United States, 92123
Actively Recruiting
3
Connecticut Office of the Chief Medical Examiner
Farmington, Connecticut, United States, 06032
Actively Recruiting
4
Peer Support Community Partners
Watertown, Massachusetts, United States, 02472
Active, Not Recruiting
Research Team
A
Alison Athey, PhD
CONTACT
K
Karen Osilla, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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