Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06854757

Families Left Behind

Led by RAND · Updated on 2025-08-21

340

Participants Needed

4

Research Sites

276 weeks

Total Duration

On this page

Sponsors

R

RAND

Lead Sponsor

S

Stanford University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The United States is facing unprecedented rates of drug overdose deaths, profoundly impacting millions of families who are left to navigate their grief. Those bereaved by overdose experience a unique form of grief characterized by feelings of guilt, shame, and blame, which can worsen their suffering and deter them from seeking help. Individuals coping with overdose loss often endure more severe health consequences compared to those grieving non-drug related deaths, including prolonged grief disorder, substance use disorders, PTSD, depression, and suicidal thoughts. Moreover, bereaved individuals, particularly those with a history of substance use, may engage in risky behaviors as a means of coping, further exacerbating the risk of overdose and mortality within this vulnerable population. Peer grief support interventions have emerged as a promising approach to assist those experiencing such losses. To combat these outcomes, we are collaborating with Peer Community Support Partners (PSCP) in a novel practice-research partnership to implement the RIVER peer grief support model. Though RIVER has shown success in community settings, it has yet to be rigorously evaluated. In a three-aim approach, this study aims to assess the effectiveness of the RIVER model while also enhancing and engaging grievers with support resources via medical examiner offices (MEOs), which routinely contact families during death investigations. This research represents a pivotal advancement in addressing the needs of the overlooked bereaved community, aligning with the NIH's Helping to End Addiction Long-term (HEAL) initiative to develop effective strategies against the opioid crisis. Together, community engagement and rigorous research efforts aim to enhance support for those affected by the tragedy of drug overdose.

CONDITIONS

Official Title

Families Left Behind

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Lost a loved one to an unintentional drug overdose within the past year
  • Age 18 years or older
  • Fluent in English or Spanish
  • Able to give consent (no severe cognitive impairment, active psychosis, or developmental disabilities)
Not Eligible

You will not qualify if you...

  • Need hospitalization for psychiatric symptoms or substance use disorders
  • Active suicidal ideation
  • Lost someone to drug overdose more than one year ago
  • Lost someone to a drug overdose death that was suicidal or of undetermined intent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Jefferson County Coroner/Medical Examiner's Office

Birmingham, Alabama, United States, 35203

Actively Recruiting

2

San Diego County Medical Examiner Office

San Diego, California, United States, 92123

Actively Recruiting

3

Connecticut Office of the Chief Medical Examiner

Farmington, Connecticut, United States, 06032

Actively Recruiting

4

Peer Support Community Partners

Watertown, Massachusetts, United States, 02472

Active, Not Recruiting

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Research Team

A

Alison Athey, PhD

CONTACT

K

Karen Osilla, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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