Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06854757

Families Left Behind: Addressing Prolonged Grief and Substance Use Disorders Among People Bereaved by Drug Overdose Deaths

Led by RAND · Updated on 2025-08-21

340

Participants Needed

4

Research Sites

213 weeks

Total Duration

On this page

Sponsors

R

RAND

Lead Sponsor

S

Stanford University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to help people who have lost a loved one to an accidental drug overdose, focusing on the unique and intense grief they experience. These individuals often face feelings like guilt, shame, and blame, which can make their grief harder and stop them from seeking support. The study is part of a larger effort to address the opioid crisis by improving grief support for those affected, especially since this group is at higher risk for prolonged grief disorder, substance use problems, PTSD, depression, and suicidal thoughts. Participants will be divided randomly into two groups. One group will be paired with a peer grief support specialist who follows the RIVER model developed by Peer Community Support Partners. They will also get a booklet with information about grief and a list of local support resources. The other group will receive just the booklet and resource list, which is considered enhanced usual care. The study will compare these two approaches to see how well the RIVER peer support helps. People in the study will be assessed at the start and then again at 3, 6, and 12 months. Researchers will measure grief symptoms, how participants cope and accept their loss, their feelings of connection, avoidance of grief reminders, substance use, depression, posttraumatic stress symptoms, and physical pain. The study seeks to understand how these supports impact participants over time and improve their wellbeing after overdose loss.

CONDITIONS

Brief Title

Families Left Behind

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Lost a loved one to an unintentional drug overdose death within the past year
  • Age 18 years or older
  • Fluent in English or Spanish
  • Able to give informed consent (no severe cognitive impairment, active psychosis, or developmental disabilities)
Not Eligible

You will not qualify if you...

  • Need for hospitalization due to psychiatric symptoms or substance use disorders
  • Active suicidal thoughts
  • Lost someone to a drug overdose death more than one year ago
  • Lost someone to a drug overdose death that was suicidal or of undetermined intent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote)

Outpatient Treatment

Duration - 12 months

Participants receive peer grief support or enhanced care as usual to address prolonged grief and substance use disorders.

1 baseline visit and 3 follow-up visits at 3, 6, and 12 months

Trial Site Locations

Total: 4 locations

1

Jefferson County Coroner/Medical Examiner's Office

Birmingham, Alabama, United States, 35203

Actively Recruiting

2

San Diego County Medical Examiner Office

San Diego, California, United States, 92123

Actively Recruiting

3

Connecticut Office of the Chief Medical Examiner

Farmington, Connecticut, United States, 06032

Actively Recruiting

4

Peer Support Community Partners

Watertown, Massachusetts, United States, 02472

Active, Not Recruiting

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Research Team

A

Alison Athey, PhD

K

Karen Osilla, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Published Research Related To This Trial

Study protocol for a randomized trial examining a peer grief support approach for people grieving drug overdose deaths.

Karen Chan Osilla, Katherine E Watkins, Tanya Lord...

https://pubmed.ncbi.nlm.nih.gov/40894007