Actively Recruiting

Phase 1
Age: 18Years +
All Genders
Healthy Volunteers
ID07239609

Acceptance and Commitment Therapy for Individuals With MNCD and Their Care Partners: An In-Person and Telehealth Individual Therapy Approach

Led by Texas Tech University · Updated on 2026-05-15

100

Participants Needed

1

Research Sites

8 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate a special therapy called Acceptance Commitment Therapy (ACT) for people diagnosed with mild neurocognitive disorder (MNCD) or mild cognitive impairment (MCI) and their care partners. Alzheimer's disease and related dementias are serious conditions that affect millions, mostly older adults, and this study focuses on helping both the individuals with these conditions and those who support them. The project looks to see if this therapy is practical, acceptable, and shows early signs of effectiveness in improving mental health and coping. The study uses ACT, a type of cognitive-behavioral therapy designed to increase psychological flexibility through six core processes like acceptance and values clarification. This therapy is provided to both the person with MNCD or MCI and their care partner, who is usually a family member or friend. The intervention is delivered in person and via telehealth, focusing on committed actions aligned with personal values rather than trying to remove difficult thoughts or feelings. Participants will be assessed during and six weeks after the therapy using various questionnaires and scales that measure depression, anxiety, grief, coping, stress, hope, sleep quality, and cognitive function. The study also examines the effects of therapy on both members of the dyad. Care partners and individuals with MNCD or MCI will communicate in English and be monitored for mental health and wellbeing outcomes. The study is expected to run until the end of 2027, with ongoing evaluation of feasibility, acceptability, and preliminary benefits.

CONDITIONS

Brief Title

ACT for Individuals With MNCD and Their Care Partners

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Person with MCI or MNCD, aged 18 years or older
  • Able to communicate in English
  • MMSE score between 21 and 27 for person with MCI or MNCD
  • Care partner aged 18 years or older
  • Care partner able to communicate in English
  • Care partner has MMSE score between 28 and 30
  • Care partner is a family member or friend of the person with MNCD
Not Eligible

You will not qualify if you...

  • Person with MCI or MNCD currently receiving therapy to reduce anxiety or depression related to dementia
  • Person with MCI or MNCD with MMSE score less than 21 or 28 and above
  • Care partner with MMSE score less than 28
  • Care partner who is a formal (paid) caregiver

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote) for screening and enrollment

Outpatient Treatment

Duration - 6 weeks

Participants receive Acceptance Commitment Therapy (ACT), a form of cognitive-behavioral therapy designed to improve psychological flexibility and coping skills for individuals with MCI or MNCD and their care partners.

Weekly therapy sessions (in-person or telehealth) for 6 weeks

Trial Site Locations

Total: 1 location

1

Texas Tech University Plaza Building

Lubbock, Texas, United States, 79409-2051

Actively Recruiting

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Research Team

J

Jonathan Singer, Ph.D.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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