Fifth Visit of the STANISLAS Cohort to Study Family Inheritance, Gene Interactions, and Environmental Effects on Cardiovascular and Kidney Diseases

What this Trial Is About

Researchers are studying cardiovascular aging and the development of heart and kidney diseases by following families originally recruited in the 1990s as part of the Stanislas Cohort. This long-term project aims to understand how genetics and environmental factors interact to affect heart and kidney health, considering metabolic syndrome components, genetic markers, lifestyle, and nutrition. The study also explores links between COVID-19 infection and cardiovascular or kidney health. Participants will undergo a range of assessments including echocardiography, lung ultrasound, blood pressure measurements, and ultrasound of arteries and veins. Biological samples such as blood and urine will be collected for genetic and biomarker analyses. Questionnaires will gather data on diet, health behaviors, anxiety, sleep quality, and COVID-19 history. Some optional procedures, like ambulatory blood pressure monitoring and pollutant analysis, are also offered. During the study visit, participants provide clinical, biological, and lifestyle information. Researchers will measure heart and blood vessel function, kidney health, metabolic parameters, and document any cardiovascular events. Various questionnaires and physical measurements will support data collection. The study includes safety and compliance checks and will continue until July 2027, focusing on long-term cardiovascular and renal aging outcomes.

FAMILY INHERITANCE, GENE-GENE AND GENE-ENVIRONMENT INTERACTIONS IN THE FIELD OF CARDIOVASCULAR AND RENAL DISEASES. Fifth Visit of the STANISLAS Cohort