Actively Recruiting
Family Inheritance, Gene-Gene and Gene-Environment Interactions in Cardiovascular and Renal Diseases: Fifth Visit of the Stanislas Cohort
Led by Central Hospital, Nancy, France · Updated on 2023-08-15
3000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying cardiovascular aging and the development of heart and kidney diseases by following families originally recruited in the 1990s as part of the Stanislas Cohort. This long-term project aims to understand how genetics and environmental factors interact to affect heart and kidney health, considering metabolic syndrome components, genetic markers, lifestyle, and nutrition. The study also explores links between COVID-19 infection and cardiovascular or kidney health. Participants will undergo a range of assessments including echocardiography, lung ultrasound, blood pressure measurements, and ultrasound of arteries and veins. Biological samples such as blood and urine will be collected for genetic and biomarker analyses. Questionnaires will gather data on diet, health behaviors, anxiety, sleep quality, and COVID-19 history. Some optional procedures, like ambulatory blood pressure monitoring and pollutant analysis, are also offered. During the study visit, participants provide clinical, biological, and lifestyle information. Researchers will measure heart and blood vessel function, kidney health, metabolic parameters, and document any cardiovascular events. Various questionnaires and physical measurements will support data collection. The study includes safety and compliance checks and will continue until July 2027, focusing on long-term cardiovascular and renal aging outcomes.
CONDITIONS
Brief Title
FAMILY INHERITANCE, GENE-GENE AND GENE-ENVIRONMENT INTERACTIONS IN THE FIELD OF CARDIOVASCULAR AND RENAL DISEASES. Fifth Visit of the STANISLAS Cohort
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged over 18
- Previously participated in the Stanislas Cohort
- Affiliated with or beneficiary of a social security scheme
- Received complete information about the study and signed informed consent
You will not qualify if you...
- Currently deprived of liberty by judicial or administrative decision
- Undergoing psychiatric treatment under Articles L. 3212-1 and L. 3213-1
- Pregnant, parturient, or breastfeeding women
- Under legal protection measures such as guardianship, curatorship, or safeguard of justice
- Unable to provide informed consent as an adult
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants complete comprehensive assessments including blood and urine sample collection, cardiovascular evaluations, anthropometric and hemodynamic measurements, and various questionnaires on diet, health history, and symptoms related to SARS-CoV-2 infection.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
CHRU de Nancy
Vandœuvre-lès-Nancy, Lorraine, France, 54500
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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