Actively Recruiting
The Influence of Electrical Acupoint Stimulation at Different Frequencies on Hemodynamics During Anesthesia Induction in Patients Undergoing TAVR Surgery
Led by Air Force Military Medical University, China · Updated on 2026-03-25
150
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how electrical stimulation at different frequencies on specific acupoints affects blood pressure changes during anesthesia induction in patients undergoing Transcatheter Aortic Valve Replacement (TAVR) surgery. The study compares the effects of high-frequency and low-frequency electrical acupoint stimulation to understand their influence on hemodynamic stability. Participants receive electrical stimulation at the Neiguan, Jian Shi, and Baihui acupoints starting 15 minutes before anesthesia induction and continuing until 15 minutes after. Two groups receive different frequencies: one group at 100Hz (high-frequency) and the other at 2Hz (low-frequency). This randomized, quadruple-blind study carefully monitors the effects during the anesthesia induction period. During the study, researchers measure the change in mean arterial pressure from induction start to 15 minutes after and record the area under the curve for this change. They also track occurrences of hypotension, dosage of vasoactive drugs used, complications such as cardiovascular events or acute kidney injury, length of hospital stay, ICU admission rates, quality of recovery, and discharge assessment scores. Participants are followed from surgery through discharge and up to 30 days post-surgery to assess overall outcomes.
CONDITIONS
Brief Title
Frequency of Electrical Acupoint Stimulation on Hypotension in TAVR Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- The age of the patients is 60 years or older
- Patients who are scheduled to undergo TAVR surgery under general anesthesia
You will not qualify if you...
- Body mass index less than 18 kg/m2 or greater than 30 kg/m2
- Hemodynamic instability such as severe arrhythmia or decompensated heart failure
- Hypotension after admission requiring intervention with vasoactive drugs
- Severe liver or kidney dysfunction
- Contraindications for electrical stimulation including local skin damage, infection, or implanted electrophysiological devices
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Approximately 30 minutes during surgery
Participants receive electrical acupoint stimulation starting 15 minutes before anesthesia induction and continuing until 15 minutes after induction during TAVR surgery.
1 surgical visit (in-person)
Duration - Up to 30 days after surgery
Participants are monitored for major complications, recovery quality, and hospital stay after surgery.
Approximately 5 days in hospital plus follow-up assessments up to 30 days
Trial Site Locations
Total: 1 location
1
Xijing Hospital, Fourth Military Medical University
Xi'an, Shannxi, China, 710032
Actively Recruiting
Research Team
Z
Zhihong Lu
H
Hailong Dong
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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