Actively Recruiting
Genetics and Biohumoral Factors Involved in Meni e8re's Disease and Vestibular Migraine
Led by IRCCS San Raffaele · Updated on 2026-04-08
250
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the role of genetic polymorphisms related to ionic transport regulation in Caucasian patients with Meni e8re's Disease (MD). This research compares genetic and biohumoral factors among patients with definite MD, patients with vestibular migraine, and a group of non-vertiginous individuals. The study aims to better understand the genetic influence on MD and its differences from vestibular migraine, as familial cases suggest a genetic and environmental interplay. Participants are grouped into those with definite Meni e8re's Disease, definite Vestibular Migraine, and non-vertiginous controls. Each participant will provide a blood sample to analyze genetic and biohumoral factors, including specific biohumoral markers like interleukins and endogenous ouabain. The study collects data from enrollment through to the end of enrollment in December 2027, with biohumoral factors monitored until July 2027. During the study, participants will undergo blood withdrawal for genetic and biohumoral testing. Researchers will measure the genetics of ionic transporters and biohumoral factors over time. The study is observational, involving no treatment intervention, and participants are monitored from enrollment until the study's conclusion. Participation involves providing consent and a blood sample, with follow-up assessments based on these biological measures.
CONDITIONS
Brief Title
Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with definite Meni�e8re's Disease according to the criteria of the Barany Society
You will not qualify if you...
- Patients who have had surgery before the examination
- Patients who have undergone intratympanic therapy with steroids or gentamicin
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Concurrent with enrollment period
Participants with definite Menière's Disease or Vestibular Migraine are identified according to the criteria of the Barany Society.
1 visit (in-person)
Duration - From enrollment until study completion in July 2027
Participants provide blood samples to assess genetic polymorphisms and biohumoral factors related to Menière's Disease and Vestibular Migraine.
1 visit for blood withdrawal
Duration - From enrollment to study completion in July 2027
Participants are observed for genetic and biohumoral factors related to their condition throughout the study period.
No additional visits required beyond sample collection
Trial Site Locations
Total: 1 location
1
IRCCS San Raffaele
Milan, Italy, Italy, 20132
Actively Recruiting
Research Team
R
Roberto Carlo Teggi, MD
L
Laura Zagato, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here