Actively Recruiting
Genetic Studies of Strabismus, Nystagmus, and Associated Disorders
Led by Boston Children's Hospital · Updated on 2025-12-12
400
Participants Needed
1
Research Sites
482 weeks
Total Duration
On this page
Sponsors
B
Boston Children's Hospital
Lead Sponsor
N
National Eye Institute (NEI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus. Three types of subects will be enrolled: (1) Families with at least 3 members with strabismus, (2) individuals with infantile esotropia and their parents and siblings, and (3) individuals with infantile nystagmus and their parents. Whole exome and/or whole genome sequencing will be used to identify genetic variants shared by family members with strabismus and to identify genetic causes of nystagmus.
CONDITIONS
Official Title
Genetic Studies of Strabismus, Nystagmus, and Associated Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be a member of a family with at least 3 biological relatives with strabismus, including both affected and unaffected members
- Be part of a family with at least 1 individual diagnosed with infantile esotropia, including both affected and unaffected members
- Be part of a family with at least 1 individual diagnosed with infantile nystagmus, including both affected and unaffected members
You will not qualify if you...
- Have paralytic strabismus in affected family members
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Boston Children's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
K
Kayleen Cremin, BA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here