Actively Recruiting
Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women
Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2026-05-12
250
Participants Needed
1
Research Sites
270 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: Heart disease is a leading cause of death in the United States. Healthy diet and exercise improve heart health. Some features of where a person lives can lead to stress and decrease chances for exercise. Researchers want to see how these factors may increase the risk of heart disease in women. Objective: To see if there are differences in stress levels between women who live in different parts of Washington, DC. Also, to see how these women use their neighborhoods for exercise. Eligibility: Healthy white or black females ages 19-45 who live in Washington, DC, who have access to a smartphone Design: Participants may stay at the NIH Clinical Center overnight for a 2-day visit. Visit 1 will include: Physical exam Blood tests Electrocardiogram: Electrodes on the participant s skin will measure heart activity. PET/CT scan: Participants will get an injection. They will lie in a machine that takes pictures of the body. Surveys Body size measurements Nutrition consultation Blood vessel tests: This is measured with blood pressure cuffs, a device placed on the participant s fingertip, and a probe placed on the participant s neck. Resting Energy Expenditure: Participants will breathe under a clear hood for 45 minutes. Participants will be followed for about 2 weeks. They will wear a device on the wrist and carry a GPS device. Through a mobile app, they will answer short daily surveys on stress and exercise. Visit 2- Device return Nutritional consultation
CONDITIONS
Official Title
Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy self-identified White or Black female
- Age between 19 and 45 years
- No chronic health conditions such as cardiovascular, autoimmune, or endocrine diseases
- Living in Washington, DC
- Access to a smartphone
- Able to provide informed consent
- English speaking
You will not qualify if you...
- Pregnant or breastfeeding
- Unable to perform physical activity
- Weight change greater than 20% in the past 3 months
- Obese with BMI ≥ 35.0 kg/m²
- High or low blood pressure requiring medication
- Diabetes
- History of severe mental illness requiring hospitalization
- Active thyroid disease requiring medication
- Taking medication for chronic non-mental health illnesses
- Food allergies or restrictive diets preventing controlled diet
- Current smoker of tobacco products
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
M
Marie Marah, R.N.
CONTACT
T
Tiffany M Powell-Wiley, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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