Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID07543705

Glucose-Level During Endurance Exercise (GLEE Study): Influencing Factors and Mechanisms

Led by University of Ulm · Updated on 2026-05-11

100

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying glucose metabolism and its influencing factors during endurance exercise in healthy soldiers. The study focuses on understanding glucose dynamics, sympathetic nervous system activation, and heart rate variability during a standardized military march. This observational research involves a well-screened group of soldiers who undergo regular health checks, making them an ideal population for investigating metabolic responses to physical exertion. Participants will complete a 6 km march carrying 15 kg of equipment while wearing sensors such as continuous glucose monitors and electrocardiography devices. Before and after the march, blood and urine samples will be collected to assess metabolic markers including catecholamine levels. Body composition will be analyzed using bioelectrical impedance, and questionnaires will gather information on fitness, lifestyle, and medical history. Throughout the study, researchers will monitor physiological and metabolic parameters at baseline, during, and immediately after the march. Data collected include glucose levels, heart rate variability, inflammatory biomarkers, cortisol, and lipolysis markers. The study aims to correlate these measurements with physical activity and body composition to better understand glucose regulation during exercise. Participation involves one assessment visit with sample collection, questionnaires, and the march, concluding with removal of sensors and final testing.

CONDITIONS

Brief Title

Glucose-Level During Endurance Exercise

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • BMI between 18.5 and 30 kg/m²
Not Eligible

You will not qualify if you...

  • Pregnancy or lactation
  • Cardiovascular disease
  • Vegan diet
  • Drug or alcohol abuse
  • Drug therapy that raises or lowers blood sugar, such as steroids, antidiabetics, or insulin, or that influences the autonomic nervous system
  • No consent to be informed about incidentally discovered pathological findings
  • Any other clinical condition that would endanger participant safety or affect scientific success according to physician opinion

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants undergo baseline assessments including questionnaires, blood and urine sample collection, body composition analysis, and sensor application for physiological monitoring.

1 baseline visit (in-person)

Monitoring

Duration - Approximately 1 hour

Participants complete a standardized 6 km military march carrying 15 kg of equipment while wearing continuous glucose and heart rate monitoring devices to assess metabolic parameters.

1 in-person exercise session

Post-exercise Assessment

Duration - Same day as exercise

After the march, sensors are removed and additional blood and urine samples are collected to evaluate metabolic and hormonal responses to physical exertion.

1 post-exercise visit (in-person)

Trial Site Locations

Total: 1 location

1

Bundeswehr Hospital Ulm

Ulm, Germany, 89081

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Research Team

M

Martin Heni, MD

S

Sabrina Wanglelr

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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