Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT06330818

Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients

Led by University Hospital Tuebingen · Updated on 2024-09-26

50

Participants Needed

1

Research Sites

178 weeks

Total Duration

On this page

Sponsors

U

University Hospital Tuebingen

Lead Sponsor

U

University Hospital Freiburg

Collaborating Sponsor

AI-Summary

What this Trial Is About

Aim of this study is to improve patient care in Moyamoya Patients by improving Imaging technologies and aiming to identify factors involved in disease progression. Main tasks are: * Analysis of CO2-triggered BOLD fMRI for analysis of cerebral hemodynamics in comparison to H2 15O PET/CT * Analysis of longitudinal changes of contrast enhancement in vessel-wall imaging and correlation of disease activity with biosampling * Definition of a standardized recommendation for pre- and postoperative imaging of Moyamoya patients

CONDITIONS

Official Title

Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with suspicion of Moyamoya Disease
  • Patients able to understand the study and to give their informed consent
Not Eligible

You will not qualify if you...

  • Cerebral vascular disease caused by atherosclerosis
  • Vasculitis
  • Contraindications to MRI
  • Contraindications to PET/CT
  • Pregnancy
  • Inability to give informed consent
  • Renal insufficiency

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Tuebingen, Neurosurgery

Tübingen, Baden-Wurttemberg, Germany, 72076

Actively Recruiting

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Research Team

C

Constantin Roder, Prof. Dr., MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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