Actively Recruiting

Age: 18Years +
All Genders
NCT06724029

Neurosurgical Outcome Network

Led by Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Updated on 2026-03-30

4500

Participants Needed

27

Research Sites

234 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared. This study aims to assess outcomes and their predictors using measures agreed upon by the participating centers. Standardizing the evaluation of outcomes and predictors improves the quality of research, allows for data comparison, and facilitates a "common language" in routine clinical practice. Most importantly, it influences therapeutic decisions in various neurosurgical conditions. Clinically, the identified predictors can also be used during preoperative assessments to provide more precise guidance to patients undergoing surgery.

CONDITIONS

Official Title

Neurosurgical Outcome Network

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of neuro-oncological pathology including supratentorial and subtentorial tumors, excluding skull base tumors
  • Diagnosis of basicranial tumors from anterior, middle, and posterior cranial fossae or sellar region
  • Diagnosis of vascular pathologies such as aneurysms, AVMs, cavernomas, Moyamoya disease, dural fistulas, or nontraumatic hematomas
  • Diagnosis of traumatic pathology including diffuse or focal brain damage, subdural hematoma, extradural hematoma, subarachnoid hemorrhage, intraparenchymal hematoma, fractures, or hydrocephalus
  • Diagnosis of spinal pathologies including degenerative cervical, myelopathic, traumatic, thoracolumbar, or oncologic spinal conditions
  • Diagnosis of functional pathologies such as Parkinson's disease, spasticity, trigeminal neuralgia, craniofacial pain, neuropathic pain, tremor, dystonias, obsessive-compulsive disorder, drug-resistant epilepsy, depression, or normotensive hydrocephalus
  • Diagnosis of peripheral nervous system conditions including nerve compression syndromes, tumors, or trauma
  • Diagnosis of malformative pathologies such as Chiari malformation type 1, craniostenoses, or malformative hydrocephalus
  • At least 18 years old
  • Adequate understanding of Italian language
  • Diagnosis of glioma, meningioma, vascular pathology, or spinal pathology for cognitive and psychological assessment
Not Eligible

You will not qualify if you...

  • History of psychiatric diseases or current use of psychotropic drugs for cognitive and psychological assessment
  • Presence of overt cognitive decline not related to the injury
  • Age younger than 18 years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 27 locations

1

1. ASST Papa Giovanni XXIII

Bergamo, BG, Italy, 24127

Active, Not Recruiting

2

Spedali Civili Brescia

Brescia, BS, Italy, 25123

Active, Not Recruiting

3

Fondazione Poliambulanza Istituto Ospedaliero

Brescia, BS, Italy, 25124

Active, Not Recruiting

4

Ospedale Moriggia Pelascini

Gravedona, Como, Italy, 22015

Active, Not Recruiting

5

ASST Lariana, Ospedale S. Anna

Como, CO, Italy, 22100

Active, Not Recruiting

6

ASST Cremona

Cremona, CR, Italy, 26100

Active, Not Recruiting

7

Fondazione IRCCS San Gerardo dei Tintori

Monza, MB, Italy, 20900

Active, Not Recruiting

8

Fondazione IRCCS Policlinico San Matteo

Pavia, PV, Italy, 27100

Active, Not Recruiting

9

ASST della Valtellina ed Alto Lario

Sondrio, SO, Italy, 23100

Active, Not Recruiting

10

Azienda Ospedaliero Universitaria Policlinico "G. Rodolico - San Marco"

Catania, Italy

Actively Recruiting

11

Azienda Ospedaliero Universitaria Careggi

Florence, Italy

Actively Recruiting

12

Ospedale F. Spaziani di Frosinone

Frosinone, Italy, 03100

Actively Recruiting

13

Ospedale Alessandro Manzoni

Lecco, Italy, 23900

Active, Not Recruiting

14

ASST Ovest Milanese

Legnano, Italy, 20025

Active, Not Recruiting

15

Ospedali Riuniti di Livorno -Azienda USL Toscana nord ovest

Livorno, Italy

Actively Recruiting

16

Fondazione IRCCS Istituto Neurologico Carlo Besta

Milan, Italy, 20133

Actively Recruiting

17

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Italy, 20122

Active, Not Recruiting

18

ASST Santi Paolo e Carlo

Milan, Italy, 20153

Actively Recruiting

19

ASST Fatebenefratelli Sacco

Milan, Italy

Active, Not Recruiting

20

Istituto Clinico Città Studi

Milan, Italy

Active, Not Recruiting

21

Policlinico di Monza

Monza, Italy, 20900

Actively Recruiting

22

A.R.N.A.S. Ospedali Civico di Palermo

Palermo, Italy, 90127

Actively Recruiting

23

Azienda Ospedaliero Universitaria di Parma

Parma, Italy

Active, Not Recruiting

24

ASL Roma 1

Roma, Italy, 00135

Actively Recruiting

25

Fondazione Policlinico Universitario Gemelli di Roma

Roma, Italy, 00168

Actively Recruiting

26

IRCCS Istituto Clinico Humanitas

Rozzano, Italy, 20089

Active, Not Recruiting

27

Azienda Sanitaria Universitaria Friuli Centrale di Udine

Udine, Italy, 33100

Actively Recruiting

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Research Team

P

Paolo Ferroli, MD

CONTACT

M

Morgan A Broggi, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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