Adverse Events in Neurosurgery: The Novel Therapy-Disability-Neurology Grade.
Alexis Paul Romain Terrapon, Costanza Maria Zattra, Stefanos Voglis...
https://pubmed.ncbi.nlm.nih.gov/33887774/Actively Recruiting
Led by Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Updated on 2026-03-30
4500
Participants Needed
27
Research Sites
N/A
Total Duration
Researchers are evaluating outcomes and their predictors in various neurosurgical conditions to improve the quality and consistency of research and clinical care. The study focuses on standardizing the assessment of clinical, cognitive, and psychological status before and after neurosurgical interventions across multiple centers. This effort aims to create a common language in routine practice and support better therapeutic decisions through shared data and identified predictive factors. The study collects detailed clinical and demographic information from patients undergoing neurosurgery for a wide range of conditions, including tumors, vascular diseases, trauma, spinal disorders, functional pathologies, peripheral nerve issues, and malformations. Data such as comorbidities, anesthesia details, complications, and psychological assessments are gathered before surgery and at follow-ups, with timing varying by condition. An artificial intelligence analysis will be used to identify important predictors and outcomes. Participants will provide data over a period of up to five years, including sociodemographic details, clinical status, cognitive and psychological assessments, and complication records. The study monitors these factors preoperatively and postoperatively to describe outcomes and explore associations with preoperative indicators. The long-term collection of data supports understanding neurosurgical results and guiding patient care more precisely.
CONDITIONS
Neurosurgical Outcome Network
P
Paolo Ferroli, MD
M
Morgan A Broggi, MD
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Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 year
Participants undergo collection of preoperative clinical, cognitive, and psychological data related to their neurosurgical pathology.
Visits as scheduled before surgery depending on pathology
Duration - Variable based on intervention and hospitalization
Participants undergo neurosurgical intervention and immediate postoperative clinical care with collection of relevant clinical data.
Hospital visits during intervention and immediate recovery period
Duration - Up to 5 years
Participants have follow-up visits to collect postoperative clinical, cognitive, and psychological data to evaluate outcomes and predictors.
Regular follow-up visits scheduled over 5 years depending on pathology
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Lead Sponsor