Actively Recruiting

Age: 5Years - 13Years
All Genders
NCT04993859

Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

Led by University of Colorado, Denver · Updated on 2025-10-15

152

Participants Needed

1

Research Sites

266 weeks

Total Duration

On this page

Sponsors

U

University of Colorado, Denver

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.

CONDITIONS

Official Title

Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

Who Can Participate

Age: 5Years - 13Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged 5 to 13 years old
  • History of cancer
  • Treated with chemotherapy including vincristine and/or doxorubicin
  • Completed chemotherapy at least one year before enrollment and survey completion
Not Eligible

You will not qualify if you...

  • Presence of a primary pelvic tumor
  • History of pelvic irradiation
  • Existing bladder or bowel dysfunction
  • Spinal defects
  • Neurologic disorders
  • Neuro-oncologic tumor or brain metastasis
  • Treatment with cyclophosphamide or ifosfamide

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Children's Hospital Colorado

Aurora, Colorado, United States, 80045

Actively Recruiting

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Research Team

G

Gemma Beltran

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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