Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06619366

The Impact of Coach-guided Risk Communication on the Risk of Major Depression

Led by Dalhousie University · Updated on 2025-09-02

1000

Participants Needed

1

Research Sites

242 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Depression is a highly prevalent and disabling mental health problem. One way of preventing depression is to stop it before it happens through effective self-management. Working with potential users, a coach-guided, personalized depression risk communication tool (PDRC) was developed for sharing information about individualized depression risk, risk profile (risk factors present), potential risk reduction and evidence-based self-help strategies. It is anticipate that the PDRC will greatly motivate users to actively engage in self-help and help seeking, leading to a reduced risk of depression. The proposed study will recruit 500 male and 500 female adults who are at high risk of having depression across Canada, and randomly allocate them into the intervention and control groups. Participants will be followed for 12 months. The data of the trial will allow us to answer the questions: (1) Can the coach-guided PDRC reduce the risk of depression? (2) Does the intervention motivate people to actively engage in evidence-based self-help and help-seeking behaviors? (3) For whom the intervention works best? and (4) what are the costs and potential savings associated with the intervention? If successful, this project will offer a novel and effective tool for early prevention of major depression in the Canadian general population, help us understand how it works and the cost-effectiveness of implementing such a tool in the community from the economic perspective.

CONDITIONS

Official Title

The Impact of Coach-guided Risk Communication on the Risk of Major Depression

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • No current major depressive episode or full remission of at least 2 months if previously had one
  • Aged between 18 and 65 years
  • At high risk of major depressive episode based on sex-specific depression risk calculators (6.5%+ for males, 11.2%+ for females)
  • Agree to be contacted for follow-up assessments
  • Able to communicate in English or French without language barriers
Not Eligible

You will not qualify if you...

  • Unable to provide informed consent
  • Do not agree to be followed during the study
  • Cannot communicate in English or French
  • Report suicide behaviors (score greater than 0 on item 9 of the Patient Health Questionnaire)

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Faculty of Medicine

Halifax, Nova Scotia, Canada, B3H 1V7

Actively Recruiting

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Research Team

J

Jianli Wang, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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