Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06951386

The Impact of Daily Intake of Short-chain Fatty Acids on Cardiometabolic Risk Factors in Individuals at Risk for Metabolic Syndrome

Led by KU Leuven · Updated on 2025-05-04

50

Participants Needed

1

Research Sites

54 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

During this study, the effect of short-chain fatty acids on blood lipaedemia, glycemia, anthropometrics, blood pressure and energy expenditure will be investigated.

CONDITIONS

Official Title

The Impact of Daily Intake of Short-chain Fatty Acids on Cardiometabolic Risk Factors in Individuals at Risk for Metabolic Syndrome

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female participants
  • Central obesity (BMI 25 25 kg/m or waist circumference 25 80 cm for women/ 25 94 cm for men)
  • At least one additional risk factor for metabolic syndrome: insulin resistance (HOMA-IR 25 1.7 or fasting glucose 25 100 mg/dl), triglyceride concentration 25 150 mg/dl, HDL cholesterol < 40 mg/dl for women or < 50 mg/dl for men, or systolic blood pressure 25 130 mmHg or diastolic blood pressure 25 85 mmHg
  • Knowledge of English
Not Eligible

You will not qualify if you...

  • Gastrointestinal disorders such as IBD, IBS, celiac disease, chronic constipation, or chronic diarrhea
  • History of abdominal surgery except appendectomy
  • Use of antihypertensive, cholesterol lowering, glucose-regulating drugs, or corticosteroids
  • Use of antibiotics within 3 months prior to or during the study
  • Use of probiotics or prebiotics within 2 weeks prior to or during the study
  • Being on weight loss, gluten-free, lactose-free, or vegan diet
  • Pregnancy, lactation, or planning to become pregnant
  • Previous or current substance or alcohol dependence or abuse
  • Hyper- or hypothyroidism
  • Allergy or intolerance to oat milk

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

KU Leuven/ UZ Leuven

Leuven, Vlaams-Brabant, Belgium, 3000

Actively Recruiting

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Research Team

R

Riet Rosseel, Msc

CONTACT

K

Kristin Verbeke, Prof.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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