Effects of Full-Fat and Low-Fat Milk Diets on Heart and Metabolic Health in Adults with Metabolic Syndrome

What this Trial Is About

Researchers are studying the effects of whole-fat dairy consumption on heart and metabolic health in adults with metabolic syndrome. The study aims to understand how this diet influences cardiovascular risk factors and the function of blood vessels in this group. The research is sponsored by Mayo Clinic and is designed as a randomized, double-blind clinical trial. Participants will follow two different diet plans a full-fat, isoenergetic diet and a low-fat, isoenergetic diet, each lasting three weeks. Both diets contain 45% carbohydrates, 20% protein, and 35% fat. Participants will switch from one diet to the other during the trial to compare their effects on health markers. During the study, researchers will measure changes in cholesterol levels, blood sugar, inflammatory markers, and vascular function at baseline, week 3, week 5, and week 8. These assessments include total cholesterol, HDL-C, LDL-C, triglycerides, blood glucose, hemoglobin A1c, C-reactive protein, lipoprotein, and both macrovascular and microvascular function. The study will monitor participants closely throughout to evaluate these outcomes and ensure safety.

A Study Of Milk Consumption In Metabolic Syndrome