Effects of Chronic Non-specific Low Back Pain on Brain Function and Thinking Abilities in Older Adults Aged 60 to 85

What this Trial Is About

Researchers are studying how chronic non-specific low back pain CNSLBP, a common condition in older adults, may affect cognitive functions, especially executive functions like memory, attention, and problem-solving. The study aims to understand whether brain changes caused by CNSLBP relate to cognitive decline, using brain imaging to explore structural and functional differences between older adults with CNSLBP and healthy peers. This observational study compares two groups older adults aged 60 to 85 with CNSLBP lasting at least 3 months and an average pain intensity of 5 or higher, and healthy controls without recent low back pain. Participants will not receive any treatment as part of the study. The study uses brain scans and cognitive tests to examine brain structure, function, and executive abilities. Participants will undergo assessments including pain intensity, mood tests, disability evaluation, and various cognitive tests performed both inside and outside of MRI scans. Additional measures like physical activity, sleep quality, and frailty status will also be collected. The study monitors brain changes and cognitive function to better understand how CNSLBP impacts older adults, with all measures taken at the baseline visit.

The Impacts of Chronic Non-specific Low Back Pain on Cognitive Functions of Older Adults