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Study of Cell and Biomarker Profiles in Head and Neck Cancer Progression and Recurrence Observational Study with Tissue and Blood Collection
Led by University of Southern California · Updated on 2026-04-28
50
Participants Needed
1
Research Sites
52 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying the cells and biomarkers linked to aggressive behavior in head and neck cancer, focusing on Human papillomavirus HPV positive Oropharyngeal Squamous Cell Carcinoma OPSCC and its spread to lymph nodes. This observational study aims to profile cancer-associated fibroblasts at a detailed single-cell level to better understand cancer progression and recurrence. Participants will undergo photography, blood sample collection, tissue collection, and medical record review. These procedures help researchers gather comprehensive information about the cancers characteristics without providing any specific treatment intervention. During the study, participants samples and medical history will be analyzed, and outcomes such as overall survival and disease-free survival will be tracked for up to five years. The study involves no treatment administration, focusing solely on observation and data collection to understand the disease better.
CONDITIONS
Brief Title
An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence
Research Team
S
Sandy Tran, MS
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