Actively Recruiting
Interest of High-speed Centrifugation for Measuring Anti-Xa Activity on Lipemic Plasma
Led by University Hospital, Strasbourg, France · Updated on 2025-10-01
150
Participants Needed
1
Research Sites
91 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Some hemostasis techniques require spectrophotometric measurements. These are then subject to interference from the sample's lipemia (postprandial, hypertriglyceridemia, etc.), which risks distorting the results; this is estimated to affect 0.5 to 2.5% of samples. This is particularly the case for anti-Xa activity, a critical test used to monitor anticoagulant treatments. To date, the HUS Hematology Laboratory does not have or is aware of any alternative method to overcome this interference, and is unable to perform anti-Xa activity when the sample has excessive lipemia. This study will evaluate, on samples from routine care artificially overloaded with lipids, the effectiveness of a high-speed centrifugation process (10,800g for 10 minutes).
CONDITIONS
Official Title
Interest of High-speed Centrifugation for Measuring Anti-Xa Activity on Lipemic Plasma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patient (≥ 18 years)
- Anticoagulated with an anti-Xa agent (UFH, LMWH, fondaparinux, danaparoid, apixaban, rivaroxaban)
- Sample sent to the HUS Hematology Laboratory for anti-Xa activity measurement as part of routine care
You will not qualify if you...
- Patient with a basal lipidemic sample
- Sample of insufficient volume
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Laboratoire d'Hématologie - Unité d'Hémostase - CHU de Strasbourg - France
Strasbourg, France, 67091
Actively Recruiting
Research Team
A
Agathe HERB, PharmD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here