Studying How Central Sensitization Affects Balance in Women with Fibromyalgia Aged 18 to 65

What this Trial Is About

This research aims to explore the connection between central sensitization and balance changes in people with fibromyalgia syndrome FMS, a condition marked by widespread chronic pain and other symptoms like fatigue and mood changes. The study focuses on understanding differences in central sensitization between patients with FMS and healthy individuals, how balance performance compares, and whether central sensitization influences static and dynamic balance in FMS patients. Fibromyalgia affects about 2% to 8% of the global population and often leads to disability and reduced quality of life due to balance disorders and pain. Participants include two groups healthy volunteers and patients diagnosed with fibromyalgia according to the American College of Rheumatology ACR 2016 criteria. The study involves a one-time evaluation using various diagnostic tests, including the Biodex Balance System to assess balance, pressure pain threshold measurements, conditioned pain modulation tests, and a slowly repeated evoked pain protocol. Additional assessments include questionnaires on pain intensity, fibromyalgia impact, anxiety, depression, quality of life, fatigue, and mobility. During the single study visit, participants will provide demographic information and undergo multiple assessments to measure pain sensitivity, balance, and related symptoms. Researchers will use tools like the Central Sensitization Inventory, Numeric Rating Scale, and Timed Up and Go test to gather data. The main outcomes measured over a five-month analysis period include pain threshold, pain modulation, and evoked pain responses. Secondary outcomes assess balance, quality of life, anxiety, depression, fatigue, and physical function. This observational study will help clarify how central sensitization affects balance in fibromyalgia patients, potentially guiding future rehabilitation approaches.

Investigation of the Relationship Between Central Sensitization and Balance in Fibromyalgia