Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT03647358

Lesion Dosimetry With Iodine-124 in Metastatic Thyroid Carcinoma

Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-04-14

60

Participants Needed

1

Research Sites

466 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate a new diagnostic imaging test, positron emission tomography (PET), with a different radioactive form of iodine called iodine-124. This form is able to accurately measure the amount of radioactive iodine uptake in the cancer. If the new test determines sufficient radioiodine uptake in the cancer, treatment will continue as usual. However, if the new test shows only low radioiodine uptake, a decision may be made that the benefit from radioiodine therapy is insufficient and that another form of therapy is preferred.

CONDITIONS

Official Title

Lesion Dosimetry With Iodine-124 in Metastatic Thyroid Carcinoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults with thyroid carcinoma confirmed by pathology
  • Adults who have undergone total thyroidectomy
  • Adults with metastatic disease or suspicion of metastatic disease, or under protocol for re-induction therapy for 131I uptake
  • Planning to receive 131I therapy if persistent radioiodine-avid metastases are present
  • Measurable disease documented within the previous six months by ultrasonography, MRI, FDG PET/CT, or CT scanning
Not Eligible

You will not qualify if you...

  • Under 18 years of age
  • Pregnant patients

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065

Actively Recruiting

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Research Team

R

Ravinder Grewal, MD

CONTACT

S

Steven Larson, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Lesion Dosimetry With Iodine-124 in Metastatic Thyroid Carcinoma | DecenTrialz