Usak Merkez

Cesarean delivery is a common surgical procedure often linked to postoperative pain, anxiety, and reduced comfort during early recovery. Researchers are evaluating the effects of aromatherapy inhalation and aromatherapy-assisted back massage on these symptoms in women after cesarean delivery. This randomized controlled trial aims to provide evidence on complementary non-drug approaches to support maternal well-being after surgery. Participants will be randomly assigned to one of three groups aromatherapy inhalation, aromatherapy-assisted back massage, or a placebo inhalation group receiving sterile water. Interventions start 6 hours after surgery and occur at 6, 18, 30, and 42 hours postoperatively. Aromatherapy uses Rosa damascena essential oil either by inhalation or mixed with carrier oil for back massage, while the placebo group receives water inhalation following the same schedule. Women in the study will have their pain, anxiety, and postpartum comfort assessed before and after each intervention session using scales like the Visual Analog Scale, State-Trait Anxiety Inventory, and Postpartum Comfort Scale. These assessments help understand the treatments effects on recovery. The study spans from 6 to 42 hours after cesarean delivery, providing detailed monitoring during the early postpartum period.

As people age, they often experience reduced physical stamina and memory functions, which can make recovering from daily physical and mental fatigue more difficult. This challenge affects their independence and overall quality of life. Researchers are investigating how levels of cognitive reserve, which is the brains resilience built through life experiences like education and social activities, influence older adults recovery from normal fatigue. Although cognitive reserve is known to protect against conditions like dementia, its role in everyday fatigue recovery is less understood. This observational study focuses on individuals aged 65 to 90, examining how their cognitive reserve levels affect their ability to cope with fatigue, need for rest, return to daily activities, and perception of recovery. Participants will be evaluated to measure their baseline cognitive reserve and how they perceive recovery from mental and physical fatigue. The study does not involve any treatments but observes these relationships to fill gaps in current knowledge. Participants will undergo assessments to determine their cognitive reserve level and complete questionnaires about their experiences with fatigue and recovery. Researchers will analyze these responses to understand how cognitive reserve influences coping and recovery. This information aims to help healthcare providers develop better, personalized rehabilitation and lifestyle support programs to improve the quality of life for older adults. The study is expected to complete by September 2026.

Researchers are studying diabetic cataract patients to understand how diabetes-related inflammation affects the eye. The study compares levels of two molecules, DEL-1 and IL-17, in the eye fluid of patients with diabetic cataracts and those with cataracts but no diabetes. DEL-1 is involved in blood vessel health and inflammation control, while IL-17 promotes inflammation and plays a role in immune response. This work aims to uncover biochemical changes linked to diabetes and eye disease. During cataract surgery, a small amount of eye fluid will be collected from both diabetic and non-diabetic patients. This fluid will be tested for DEL-1 and IL-17 levels using a laboratory method called ELISA. The study includes two groups diabetic cataract patients who have had diabetes for at least five years, and non-diabetic cataract patients. The collection occurs before any surgical fluid is added to the eye. Participants will undergo cataract surgery with sampling of eye fluid during the operation. Researchers will measure DEL-1 and IL-17 levels and look for relationships between these molecules and factors like blood sugar control HbA1c and patient demographics. The study assesses these markers during the surgery period, aiming to better understand inflammation in diabetic eye disease. The total participation involves the scheduled surgery and perioperative assessments.

Researchers are studying the effects of exercise therapy on musculoskeletal pain and quality of life in people starting isotretinoin treatment, a vitamin A derivative used for severe acne. Isotretinoin can cause side effects including acute sacroiliitis, a painful inflammation of the sacroiliac joints. This study aims to explore how stretching and sacroiliac mobilization exercises may help reduce these side effects and improve daily life for patients. Participants will be randomly assigned to one of two groups one group will follow an 18-week exercise program focusing on stability, strength, and mobility with five sessions per week divided into three 6-week phases the other group will receive no exercise intervention and only take the medication. The exercise program includes foundational strength, low-impact cardio, core and hip stability, mobility, and full body integration exercises. The study will follow patients over six months with evaluations at baseline, 1 month, 3 months, and 6 months after starting isotretinoin. Researchers will measure musculoskeletal pain using a pressure algometer device and assess quality of life with the WHOQOL-Short Form questionnaire. Pain levels will also be tracked using a visual analogue scale. The study will compare these outcomes between the exercise and control groups to assess the impact of the exercise program on isotretinoin-related side effects.

Notalgia Paresthetica NP is a chronic sensory nerve condition causing itching, burning pain, and skin discoloration on the back near the shoulder blades. This condition results from nerve compression in the thoracic spine and often affects sleep and daily life. Current treatments include creams, medications, and injections, but many patients find them unsatisfactory. This trial evaluates High-Power Laser Therapy HPLT as an additional treatment to standard care for reducing symptoms and improving quality of life in NP patients. The study involves two groups one receiving active High-Power Laser Therapy and the other receiving a sham laser procedure without therapeutic energy. The HPLT uses a 1064 nm wavelength laser at 10 watts applied over the affected back muscles and skin area for 10 minutes per session, three times per week, for four weeks total 12 sessions. The sham group undergoes the same procedure without active laser energy to maintain blinding. Participants will be assessed for pain and itching levels at the start, after three weeks, and at three months using validated scales. Researchers will also monitor quality of life and skin changes. The study is randomized and assessor-blinded to compare the effects of HPLT versus sham treatment. Participation lasts about three months, including treatment and follow-up assessments to evaluate symptom changes and safety.

Researchers are evaluating the effect of local peloid therapy on pain and jaw function in adults diagnosed with temporomandibular joint dysfunction TMD. This condition causes pain, difficulty chewing, limited jaw movement, and sometimes referred ear pain. The study aims to provide evidence about the potential benefits of peloid therapy, a heat-based treatment used in physical medicine, for improving symptoms in TMD patients. Participants will receive local peloid therapy applied externally on the temporomandibular joint area and nearby chewing muscles. The treatment consists of 10 sessions over two weeks, with five 20-minute sessions per week. A trained investigator will administer the therapy following a standardized protocol during this period. Throughout the study, participants will be assessed before and after treatment using validated clinical scales that measure jaw function, pain intensity, symptom severity, mouth opening, and secondary ear pain. The main outcome is the change in jaw function score after two weeks. The study includes close monitoring of pain and functional changes to better understand peloid therapys role in managing TMD.

This research aims to evaluate how music listening and breathing exercises during labor affect pain perception, birth expectations, and satisfaction in first-time pregnant women. Conducted in a hospital delivery unit in Turkeys Inner Aegean Region, the trial included 90 healthy primiparous women admitted for vaginal delivery. Participants were randomly assigned to one of three groups a music intervention group, a breathing exercise group, or a control group receiving routine care. In the music intervention group, women were introduced to 12 selected music tracks at 36 weeks of pregnancy during childbirth preparation classes. These tracks were shared via WhatsApp for regular listening before labor, with reminders sent every few days. During labor, participants could listen to music freely and specifically at 4, 6, and 8 cm cervical dilation for 20 minutes each time. The breathing exercise group learned Lamaze breathing techniques during prenatal classes and practiced them throughout labor, including guided sessions at the same cervical dilation points. The control group received standard maternity care without additional interventions, but pain was assessed at the same timepoints across all groups. Participants were assessed for pain intensity using the Visual Analog Scale VAS before and after music sessions or breathing exercises during labor. The duration of each labor stage was recorded, and within 6 to 12 hours after delivery, women completed scales measuring birth expectations and satisfaction. Sociodemographic data and pain scores were collected to understand how these non-drug methods might influence the childbirth experience and maternal comfort.

Meralgia Paresthetica MP is a nerve condition causing burning pain, tingling, and numbness on the outer thigh due to pressure on the lateral femoral cutaneous nerve. Common causes include obesity, pregnancy, tight clothing, weight changes, and trauma. Many patients have persistent symptoms that do not improve with standard treatments like lifestyle changes, medications, or physical therapy, and surgery carries risks. This trial aims to study the effects of High-Power Laser Therapy HPLT as an added treatment for chronic MP to see if it improves pain and function better than a sham laser procedure. Participants will receive either active HPLT or a sham laser, both delivered using a slow scanning technique over the nerve area near the hip and thigh. The active laser uses 10 Watts of continuous power with an energy dose around 800 Joules per session, while the sham device looks and sounds like it is working but emits no real energy. All participants also receive standard conservative care, which includes education on avoiding tight clothing, weight loss advice, posture changes, and home stretching exercises targeting hip muscles. During the study, participants will be monitored at baseline, 3 weeks, and 3 months to measure changes in pain intensity using the PainDETECT tool. Researchers will assess sensory symptoms and functional capacity alongside pain. The study is randomized and assessor-blinded to compare the real laser therapy against the sham. Participation involves attending scheduled visits for treatment and assessments over several months, with safety and outcomes carefully tracked throughout.