Actively Recruiting

Age: 18Years +
All Genders
NCT07078227

Long-term Follow-up of Depressive Disorders in Psychiatric Care

Led by Region Skane · Updated on 2026-04-30

415

Participants Needed

2

Research Sites

82 weeks

Total Duration

On this page

Sponsors

R

Region Skane

Lead Sponsor

L

Lund University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The project investigates long-term prognosis and predictors of treatment outcomes for difficult-to-treat depression in patients in secondary psychiatric care. The current patient cohort was collected in 2012-2021 in the study "Pharmacogenetics in patients with depression with specific focus on difficult-to-treat depression, suicide attempt and CYP2D6". The cohort consists of 415 patients, examined carefully regarding diagnostic assessment and earlier treatment. All participants were also genotyped for the drug metabolizing enzymes CYP2D6 and CYP2C19. Blood samples were stored in biobank for other analyses linked to prognostic markers. The patient cohort will now be followed up with a review of medical records and extraction of register data for a period of 5 years after their participation in the original study. The purpose of the study is to improve treatment and increase knowledge about long-term prognosis in difficult-to-treat depression. This is done by examining symptom profiles, monitoring clinical course and suicidality, and examining prognostic markers.

CONDITIONS

Official Title

Long-term Follow-up of Depressive Disorders in Psychiatric Care

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participation in the study "Pharmacogenetics in depressive patients with specific focus on difficult-to-treat depression, suicide attempt and CYP2D6"
Not Eligible

You will not qualify if you...

  • Not wanting to participate in the follow-up study

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Psychiatry Reserach Unit

Lund, Sweden, 221 85

Active, Not Recruiting

2

Research Unit, Office of Psychiatricy, habilitation and technical aid

Lund, Sweden, 221 85

Actively Recruiting

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Research Team

M

Marie Asp, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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