Internal derangements of the temporomandibular joint. Pathological variations.
C H Wilkes
https://pubmed.ncbi.nlm.nih.gov/2923691Actively Recruiting
Led by Karolinska Institutet · Updated on 2025-12-17
91
Participants Needed
1
Research Sites
12 weeks
Total Duration
K
Karolinska Institutet
Lead Sponsor
K
Karolinska University Hospital
Collaborating Sponsor
Researchers are evaluating the long-term outcomes of surgical treatment for temporomandibular joint (TMJ) disc displacement, either with reduction (DDwR) or without reduction (DDwoR). The study focuses on whether the surgical results seen six months after surgery remain stable about 10 years later, and how joint degeneration changes over time after surgery. This research addresses a gap in knowledge about the long-term effects of TMJ surgeries such as arthroscopy and discectomy, which have previously been studied mostly over shorter periods. The study involves patients who had TMJ surgery between 2014 and 2017, including arthroscopic lysis and lavage with saline irrigation or open discectomy where the joint disc is completely removed. These patients will be invited for a follow-up clinical examination and a cone-beam computed tomography (CBCT) scan of the TMJ approximately 10 years after their surgery. The examination will assess both subjective outcomes like pain and disability and objective measures such as mouth opening and joint movement. Participants will undergo a one-time visit lasting about 30 minutes for clinical evaluation and imaging. Researchers will collect data on mouth opening capacity, patient-reported pain and disability, and radiological changes compared to initial scans before surgery. The study aims to identify predictors of long-term surgical success and examine how joint degeneration correlates with clinical outcomes. All scans will be reviewed by a radiology specialist, and findings may influence future follow-up protocols. The study is observational and does not involve additional treatments.
CONDITIONS
Long-term Follow up of TMJ Surgery and Evaluation of the 6-month Control as a Prognostic Marker.
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Occurs between 2014 and 2017
Participants underwent arthroscopy or discectomy surgery of the temporomandibular joint between 2014 and 2017.
Surgery visit (in-person)
Duration - 6 months
Participants were followed up for six months post-surgery to assess early surgical outcomes including mouth opening capacity, TMJ pain, and disability.
Multiple visits during 6-month postoperative period
Duration - Approximately 1 day for clinical and radiological examination scheduled in 2025
Participants are invited for a clinical and radiological examination approximately 10 years after surgery to evaluate long-term surgical outcomes and joint status.
1 visit (in-person) including clinical assessment and CBCT radiological examination
Total: 1 location
1
Karolinska Institutet
Huddinge, Sweden, 14104
Actively Recruiting
M
Mattias Ulmner, DDS, PhD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
C H Wilkes
https://pubmed.ncbi.nlm.nih.gov/2923691M Ulmner, C Kruger Weiner, B Lund
https://pubmed.ncbi.nlm.nih.gov/31564479Mattias Ulmner, Rachael Sugars, Aron Naimi-Akbar...
https://pubmed.ncbi.nlm.nih.gov/33396653Mattias Ulmner, Tore Bjørnland, Annika Rosén...
https://pubmed.ncbi.nlm.nih.gov/38400536B Sorel, J F Piecuch
https://pubmed.ncbi.nlm.nih.gov/11030395Eric Schiffman, Richard Ohrbach, Edmond Truelove...
https://pubmed.ncbi.nlm.nih.gov/24482784Hanna Salé, Fredrik Bryndahl, Annika Isberg
https://pubmed.ncbi.nlm.nih.gov/23249569K I Murakami, Y Tsuboi, K Bessho...
https://pubmed.ncbi.nlm.nih.gov/9578253K Murakami, N Segami, M Okamoto...
https://pubmed.ncbi.nlm.nih.gov/11467389Bodil Lund, Mattias Ulmner, Tore Bjørnland...
https://pubmed.ncbi.nlm.nih.gov/31996510