Actively Recruiting

Age: 28Days - 12Months
All Genders
ID06506474

Low-value Care and Variation in Practice for Children Hospitalized With Bronchiolitis A Multicentric Prospective Observational Study

Led by St. Justine's Hospital · Updated on 2025-07-23

3000

Participants Needed

15

Research Sites

56 weeks

Total Duration

On this page

Sponsors

S

St. Justine's Hospital

Lead Sponsor

C

Children's Hospital of Eastern Ontario

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are investigating the use of low-value healthcare services in infants aged 1 to 12 months hospitalized with bronchiolitis. Low-value care refers to medical services where the harms or costs outweigh the benefits, which can lead to unnecessary procedures and stress for children. This prospective observational study aims to measure how often six specific low-value services are used, their costs, and the variability in their use across different patients, doctors, and hospitals in Canada. The study also examines whether patient and family characteristics contribute to differences in care. The study focuses on six low-value health services: respiratory virus testing, chest x-rays, continuous pulse oximetry, short-acting beta-agonists, systemic corticosteroids, and antibiotics. Data will be collected from medical records of infants admitted to pediatric wards at 15 Canadian hospitals. Participants will complete two questionnaires—one during the child’s hospital stay and another 30 days after discharge—to gather information about additional medical care and perceptions of the care received. During the study, researchers will review infants’ medical charts and collect information on treatments, hospital stay length, ICU transfers, mechanical ventilation use, and other health outcomes. Parents will provide input on shared decision-making and involvement in care decisions. The main measure is the proportion of patients receiving each low-value service over 24 months. This study aims to improve understanding of bronchiolitis care and guide efforts to reduce unnecessary treatments.

CONDITIONS

Brief Title

Low-value Care, and Variation in Practice for Children Hospitalized With Bronchiolitis

Who Can Participate

Age: 28Days - 12Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged over 28 days to under 12 months
  • Children admitted to a pediatric inpatient ward with an admission diagnosis of bronchiolitis
Not Eligible

You will not qualify if you...

  • Children previously recruited for the study during a previous bronchiolitis admission or the same illness episode at another study site

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Duration of hospital stay

Participants undergo diagnostic assessments including respiratory virus testing, chest x-rays, and continuous pulse oximetry to evaluate bronchiolitis and identify use of low-value health services.

1 hospital admission with assessments during stay

Long-term Monitoring

Duration - 30 days post-discharge

Participants are monitored through follow-up questionnaires and medical record reviews to assess additional medical care required after hospital discharge and outcomes related to bronchiolitis.

2 follow-up contacts (one during admission and one at 30 days post-discharge)

Trial Site Locations

Total: 15 locations

1

Alberta Children's Hospital

Calgary, Alberta, Canada, T3B 6A8

Actively Recruiting

2

Stollery Children's Hospital

Edmonton, Alberta, Canada, T6G 2B7

Not Yet Recruiting

3

British Columbia Children's Hospital

Vancouver, British Columbia, Canada, V6H 3N1

Actively Recruiting

4

IWK Health

Halifax, Nova Scotia, Canada, B3K 6R8

Active, Not Recruiting

5

McMaster Children's Hospital

Hamilton, Ontario, Canada, L8N 3Z5

Actively Recruiting

6

Kingston Health Science Centre

Kingston, Ontario, Canada, K7L 2V7

Not Yet Recruiting

7

Children's Hospital of Western Ontario (London Health Science Centre)

London, Ontario, Canada, N6C 0B2

Not Yet Recruiting

8

Lakeridge Health

Oshawa, Ontario, Canada, L1G 8A2

Actively Recruiting

9

Children's Hospital of Eastern Ontario

Ottawa, Ontario, Canada, K1H 8L1

Not Yet Recruiting

10

Hospital for Sick Children

Toronto, Ontario, Canada, M5G 1E8

Not Yet Recruiting

11

Centre hospitalier Cité-de-la-Santé

Laval, Quebec, Canada, H7M 3L9

Actively Recruiting

12

Hôpital Maisonneuve-Rosemont

Montreal, Quebec, Canada, H1T 2M4

Actively Recruiting

13

CHU Sainte-Justine

Montreal, Quebec, Canada, H3T 1C5

Actively Recruiting

14

Montreal Children's Hospital

Montreal, Quebec, Canada, H4A 3J1

Not Yet Recruiting

15

Centre Hospitalier Université Laval - Centre Mère-Enfant Soleil

Québec, Quebec, Canada, G1V 4G2

Active, Not Recruiting

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Research Team

O

Olivier Drouin, MD, MSc, MPH

T

Tamara Perez, MSc

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

15

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