Prediction of autonomic dysreflexia during urodynamics: a prospective cohort study.
Matthias Walter, Stephanie C Knüpfer, Jacquelyn J Cragg...
https://pubmed.ncbi.nlm.nih.gov/29650001Actively Recruiting
Led by University of Zurich · Updated on 2025-04-03
7000
Participants Needed
1
Research Sites
N/A
Total Duration
Lower urinary tract dysfunction affects patients with neurological diseases or injuries and often leads to symptoms that negatively impact their quality of life. This condition includes problems such as detrusor overactivity, detrusor sphincter dyssynergia, voiding dysfunction, and stress incontinence. Treatments can be challenging because conventional options may not always be successful. The study collects data to better understand and manage this condition in patients treated at the University of Zurich. The research involves prospectively gathering clinical, video-urodynamic, and radiological information from patients with neurogenic lower urinary tract dysfunction at the University of Zurich. There are no specific treatment interventions in this observational study; instead, data on patient conditions and outcomes are systematically recorded over time. This allows long-term follow-up to help maintain continence and preserve kidney function. Participants provide written informed consent and undergo urodynamic examinations as part of their care. Researchers collect various clinical and imaging data to monitor patients' health status, including survival from the first visit until death. The study supports ongoing evaluation of patient outcomes and treatment effectiveness through a structured database, with a planned end date in January 2030.
CONDITIONS
Lower Urinary Tract Dysfunction Database
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Initial assessment period
Participants undergo clinical, video-urodynamic, and radiological assessments to characterize their lower urinary tract dysfunction.
1 to 2 visits depending on clinical needs
Duration - Up to several years until study completion
Participants are followed over time to monitor their condition and treatment outcomes, including survival from the first visit until death.
Ongoing visits as clinically indicated
Total: 1 location
1
Spinal Cord Injury Center & Research, University of Zürich, Balgrist University Hospital
Zurich, Canton of Zurich, Switzerland, 8008
Actively Recruiting
T
Thomas M Kessler, MD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Matthias Walter, Stephanie C Knüpfer, Jacquelyn J Cragg...
https://pubmed.ncbi.nlm.nih.gov/29650001Lorenz Leitner, Sharmistha Guggenbühl-Roy, Stephanie C Knüpfer...
https://pubmed.ncbi.nlm.nih.gov/27106070