Pancreas volumes in humans from birth to age one hundred taking into account sex, obesity, and presence of type-2 diabetes.
Y Saisho, A E Butler, J J Meier...
https://pubmed.ncbi.nlm.nih.gov/17879305Actively Recruiting
Led by National Cheng-Kung University Hospital · Updated on 2023-05-12
50
Participants Needed
1
Research Sites
N/A
Total Duration
This observational study investigates the effects of different surgical methods on patients with traumatic pancreas transection. It aims to understand whether pancreas-preserving surgery can reduce the chance of developing diabetes after surgery and to identify the main causes of complications and death following pancreas transection. The study is retrospective and analyzes patient records from National Cheng Kung University Hospital, focusing on the clinical outcomes related to pancreas injuries. Patients included in the study underwent various surgical treatments depending on their condition and the surgeon's preference. These included distal pancreatectomy with or without spleen removal, or pancreas-preserving pancreatojejunostomy, performed either openly or laparoscopically. Early pancreas surgery is considered if done within 48 hours of injury, otherwise it is delayed. Procedures such as damage-control laparotomy and trans-arterial embolization were used for managing critical bleeding before pancreas surgery. Drains were placed near the pancreas stump and removed based on specific drainage criteria. Participants' medical records were reviewed for demographic data, injury details, surgical procedures, complications classified by severity, timing of drain removal, hospital stay length, and mortality. Measures like blood glucose and HbA1c levels were evaluated up to 6 months post-surgery to monitor diabetes development. The study also tracked postoperative complications and outcomes related to the drains up to 4 weeks after removal. This comprehensive follow-up helps understand the risks and recovery related to traumatic pancreas transection.
CONDITIONS
Management of Traumatic Pancreas Transection
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You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Hospital stay duration varies per patient
Participants undergo pancreas surgery, which may involve pancreas-preserving surgery or pancreatectomy, followed by immediate post-operative care including drain placement and monitoring.
1 surgical visit and daily hospital monitoring
Duration - 2 to 4 weeks
Participants are monitored after surgery for complications, drain removal, and recovery including assessment of blood glucose and pancreatic enzyme levels.
Approximately 6 post-operative visits
Duration - Up to 6 months
Participants are followed for up to 6 months to assess long-term outcomes such as post-operative diabetes.
Periodic visits during follow-up
Total: 1 location
1
National Cheng Kung University Hospital
Tainan, Taiwan, 704
Actively Recruiting
E
Edgar D. Sy, MD
C
Chih-Jung Wang, MD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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