Actively Recruiting

Age: 1Year - 70Years
All Genders
ID05856474

Surgical Management of Traumatic Pancreas Transection

Led by National Cheng-Kung University Hospital · Updated on 2023-05-12

50

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This observational study investigates the effects of different surgical methods on patients with traumatic pancreas transection. It aims to understand whether pancreas-preserving surgery can reduce the chance of developing diabetes after surgery and to identify the main causes of complications and death following pancreas transection. The study is retrospective and analyzes patient records from National Cheng Kung University Hospital, focusing on the clinical outcomes related to pancreas injuries. Patients included in the study underwent various surgical treatments depending on their condition and the surgeon's preference. These included distal pancreatectomy with or without spleen removal, or pancreas-preserving pancreatojejunostomy, performed either openly or laparoscopically. Early pancreas surgery is considered if done within 48 hours of injury, otherwise it is delayed. Procedures such as damage-control laparotomy and trans-arterial embolization were used for managing critical bleeding before pancreas surgery. Drains were placed near the pancreas stump and removed based on specific drainage criteria. Participants' medical records were reviewed for demographic data, injury details, surgical procedures, complications classified by severity, timing of drain removal, hospital stay length, and mortality. Measures like blood glucose and HbA1c levels were evaluated up to 6 months post-surgery to monitor diabetes development. The study also tracked postoperative complications and outcomes related to the drains up to 4 weeks after removal. This comprehensive follow-up helps understand the risks and recovery related to traumatic pancreas transection.

CONDITIONS

Brief Title

Management of Traumatic Pancreas Transection

Who Can Participate

Age: 1Year - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with pancreas injury confirmed by laparotomy
Not Eligible

You will not qualify if you...

  • Negative pancreas injury confirmed by laparotomy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Surgery and Immediate Post-operative Care

Duration - Hospital stay duration varies per patient

Participants undergo pancreas surgery, which may involve pancreas-preserving surgery or pancreatectomy, followed by immediate post-operative care including drain placement and monitoring.

1 surgical visit and daily hospital monitoring

Post-operative Follow-up

Duration - 2 to 4 weeks

Participants are monitored after surgery for complications, drain removal, and recovery including assessment of blood glucose and pancreatic enzyme levels.

Approximately 6 post-operative visits

Long-term Monitoring

Duration - Up to 6 months

Participants are followed for up to 6 months to assess long-term outcomes such as post-operative diabetes.

Periodic visits during follow-up

Trial Site Locations

Total: 1 location

1

National Cheng Kung University Hospital

Tainan, Taiwan, 704

Actively Recruiting

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Research Team

E

Edgar D. Sy, MD

C

Chih-Jung Wang, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Published Research Related To This Trial

Resection of complex pancreatic injuries: Benchmarking postoperative complications using the Accordion classification.

Jake E Krige, Eduard Jonas, Sandie R Thomson...

https://pubmed.ncbi.nlm.nih.gov/28396721