Actively Recruiting
Effectiveness of a Multilevel Integrated Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans
Led by Louisiana State University Health Sciences Center in New Orleans · Updated on 2026-05-11
250
Participants Needed
2
Research Sites
52 weeks
Total Duration
On this page
Sponsors
L
Louisiana State University Health Sciences Center in New Orleans
Lead Sponsor
N
National Institute on Minority Health and Health Disparities (NIMHD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
African Americans experience the highest rates of lung cancer and related deaths compared to other groups. This research evaluates a multilevel intervention that combines low-dose computed tomography (LDCT) lung cancer screening with smoking cessation efforts, aiming to reduce health disparities among African American smokers. The study follows NIH strategies addressing health determinants across different life stages to better understand and improve lung cancer prevention in this population. The intervention involves a behavioral program based on the Social Ecological Model targeting individual, institutional, and community levels. Participants are randomly assigned to either receive this multilevel intervention or usual care with no intervention. The study compares the effects of these approaches on tobacco abstinence and lung cancer screening uptake, measuring changes at baseline, immediately after the intervention, and at six months. Participants will be monitored through assessments of smoking behavior, nicotine dependence, and lung cancer screening intent and completion. Key measures include point-prevalence abstinence rates, daily cigarette use, stage of change for quitting smoking, and LDCT screening uptake. These evaluations occur at multiple time points to track progress and outcomes over the study period. The trial aims to provide scalable strategies to improve lung cancer screening and smoking cessation within African American communities.
CONDITIONS
Brief Title
Multilevel Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans
Who Can Participate
Eligibility Criteria
You may qualify if you...
- African American
- 20 or more pack years of smoking
- Eligible for or have received LDCT screening
- Current smoker
- English speaking
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Duration of the intervention period (exact duration not specified)
Participants receive a multilevel behavioral intervention targeting smoking cessation and may undergo LDCT lung cancer screening as part of the study.
Visits occur at baseline, immediately post-intervention, and 6-month follow-up
Duration - Up to 6 months post-intervention
Participants are followed up to assess smoking cessation status, lung cancer screening uptake, and related outcomes.
Follow-up visits at 6 months
Trial Site Locations
Total: 2 locations
1
LSUHSC School of Public Health
New Orleans, Louisiana, United States, 70112
Actively Recruiting
2
University Medical Center
New Orleans, Louisiana, United States, 70112
Actively Recruiting
Research Team
J
Jessica Kassner, MS, MPH
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
PREVENTION
Number of Arms
2
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