Actively Recruiting
Led by Association Clinique Thérapeutique Infantile du val de Marne · Updated on 2026-04-28
10000
Participants Needed
1
Research Sites
N/A
Total Duration
A
Association Clinique Thérapeutique Infantile du val de Marne
Lead Sponsor
P
Pfizer
Collaborating Sponsor
Researchers are conducting a national observational study to understand bacterial meningitis in children and newborns. This study focuses on the bacteria that cause meningitis, how vaccination has influenced its occurrence, and the treatment outcomes in children under 18 who are hospitalized with this condition. The goal is to describe the changing epidemiology of bacterial meningitis, especially in the context of vaccine use. The study collects detailed data on hospitalized children including risk factors, vaccination status, symptoms, and treatments given during hospital stays. Laboratory analyses such as cerebrospinal fluid cultures, antigen tests, blood cultures, and PCR are used to identify the bacteria involved. The study also tracks cases of purpura fulminans, a serious complication related to bacterial infections. Participants will be monitored during their hospital stay with focus on mortality before discharge, treatment failures 48 hours after antibiotics and repeat lumbar puncture, and the impact of vaccines. Data on clinical signs and laboratory results are collected to support the study. The study began in 2001 and continues to gather information to improve understanding of bacterial meningitis in this population.
CONDITIONS
National Bacterial Meningitis Study in Children and Newborns
You may qualify if you...
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Duration of hospitalization
Participants who undergo routine hospital care for bacterial meningitis are observed. Data on risk factors, vaccination status, signs and symptoms, and treatment during hospitalization are collected.
Visits as part of routine hospital care
Total: 1 location
1
ACTIV
Créteil, France
Actively Recruiting
C
Corinne Levy, MD
S
Stephane Bechet
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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