Actively Recruiting

Phase Not Applicable
Age: 18Years - 99Years
All Genders
Healthy Volunteers
NCT03475173

New Non-invasive Modalities for Assessing Retinal Structure and Function

Led by Randy Kardon · Updated on 2025-11-24

500

Participants Needed

1

Research Sites

460 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study investigates a new technology to assess the structure and function inside the eye. Retinal imaging of subjects with inner and outer retinal defects to detect areas of abnormal structure and function compared to other visual function tests.

CONDITIONS

Official Title

New Non-invasive Modalities for Assessing Retinal Structure and Function

Who Can Participate

Age: 18Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 99 years
  • Normal eye exam within the last 2 years for control participants
  • Defined structural defect for inner retina defect participants including ischemic optic neuropathy, branch retinal artery occlusion, hemianopia or visual field defect respecting vertical meridian, inherited mitochondrial optic neuropathies such as Leber's and Dominant Optic Neuropathy, other retinopathies or optic neuropathies
  • Diagnosis of acute zonal occult outer retinopathy or other focal or diffuse outer photoreceptor loss of function for outer retina defect participants
  • Mild cataracts allowed
Not Eligible

You will not qualify if you...

  • Cataract or media opacity that degrades retinal imaging (excluding mild cataracts)
  • Any retina or optic nerve abnormalities affecting retinal metabolism outside of normal for control participants
  • Cataract or media opacity that degrades retinal imaging for inner and outer retina defect participants

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Iowa Department of Ophthalmology

Iowa City, Iowa, United States, 52242

Actively Recruiting

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Research Team

J

Julie K Nellis, BSN

CONTACT

J

Jan M Full, BSN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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