Actively Recruiting
Non-Narcotic Pain Control After ACL Reconstruction
Led by The Cleveland Clinic · Updated on 2025-08-11
30
Participants Needed
3
Research Sites
76 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses taken and documenting the number of patients with no exposure to any narcotics (take zero oxycodone) after undergoing primary knee ACL reconstruction outpatient surgery.
CONDITIONS
Official Title
Non-Narcotic Pain Control After ACL Reconstruction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provision of signed and dated informed consent form
- Willingness to comply with all study procedures and be available for the entire study duration
- Male or female aged 15 to 55 years
- Scheduled for primary autograft ACL surgery
- Ability to take oral medication and willingness to participate in virtual follow-up pill counts at 1 and 2 weeks
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 3 locations
1
Cleveland Clinic Coral Springs
Coral Springs, Florida, United States, 33067
Active, Not Recruiting
2
Cleveland clinic sports medicine
Garfield, Ohio, United States, 44125
Actively Recruiting
3
Cleveland Clinic
Strongsville, Ohio, United States, 44136
Actively Recruiting
Research Team
J
Jennifer Baldwin
CONTACT
N
Nick Niehart
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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