Actively Recruiting

Phase Not Applicable
Age: 15Years - 65Years
All Genders
NCT06050369

Objective Characterizatoion of Repetitive Behaviors

Led by Institut National de la Santé Et de la Recherche Médicale, France · Updated on 2026-02-12

50

Participants Needed

3

Research Sites

208 weeks

Total Duration

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AI-Summary

What this Trial Is About

Introduction: Repetitive behaviors (RB) constitute a broad range of symptoms across different psychiatric/neurologic disorders. The most famous are stereotypies (found in autism), compulsions (found in obsessive-compulsive-disorder, OCD) and tics (found in Gilles de la Tourette syndrome, GTS). For some patients, it is sometime difficult to distinguish the nature of the repetitive behaviors presented, however this distinction is crucial in order to chose the appropriate treatment. Aim: In our study, the investigators will try to define electrophysiological and accelerometric marker of both OCD and tics to allow objective distinction between both tics and compulsions. Method: Subjects: Both OCD and GTS patients will be recruited, 25 patients in each group. Protocol: our study protocol will involve two step: a step in laboratory, another step at patient home. * first step: both patients group will be recorded through a high density EEG and a portative EEG while doing a task of symptom provocation. Then they will get an anatomical MRI for source recontruction. Finally, the patients will have to mimic their symptom while wearing an accelerometer (a smartwatch). * second step: both patient groups will be recorded at home through a portative EEG while tagging their symptom through a smartwatch (also used for accelerometry). After the recording, the patients will keep the smartwatch for 2 weeks, still tagging their sympoms (compulsions or tics).

CONDITIONS

Official Title

Objective Characterizatoion of Repetitive Behaviors

Who Can Participate

Age: 15Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be between 15 and 65 years old
  • Have Obsessive-Compulsive Disorder and/or Gilles de la Tourette Syndrome (including related depressive, anxious, or ADHD conditions)
  • Be registered with French social security or an equivalent
  • Provide written consent to participate
  • Women must use contraception or not be sexually active
Not Eligible

You will not qualify if you...

  • Have any psychiatric disorders other than those listed in inclusion criteria
  • Have any neurological disorders other than Gilles de la Tourette Syndrome
  • Be unable to make decisions for themselves
  • Be pregnant
  • Have contraindications for MRI
  • Not speak French

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 3 locations

1

Hôpital Albert Chenevier

Créteil, France, 94000

Actively Recruiting

2

Hôpital Henri Mondor

Créteil, France, 94010

Actively Recruiting

3

Hôpital Pitié Salpêtrière

Paris, France, 75013

Actively Recruiting

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Research Team

L

Luc MALLET, MD

CONTACT

H

Hugues LAMOTHE, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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