Actively Recruiting
Objective Characterizatoion of Repetitive Behaviors
Led by Institut National de la Santé Et de la Recherche Médicale, France · Updated on 2026-02-12
50
Participants Needed
3
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Introduction: Repetitive behaviors (RB) constitute a broad range of symptoms across different psychiatric/neurologic disorders. The most famous are stereotypies (found in autism), compulsions (found in obsessive-compulsive-disorder, OCD) and tics (found in Gilles de la Tourette syndrome, GTS). For some patients, it is sometime difficult to distinguish the nature of the repetitive behaviors presented, however this distinction is crucial in order to chose the appropriate treatment. Aim: In our study, the investigators will try to define electrophysiological and accelerometric marker of both OCD and tics to allow objective distinction between both tics and compulsions. Method: Subjects: Both OCD and GTS patients will be recruited, 25 patients in each group. Protocol: our study protocol will involve two step: a step in laboratory, another step at patient home. * first step: both patients group will be recorded through a high density EEG and a portative EEG while doing a task of symptom provocation. Then they will get an anatomical MRI for source recontruction. Finally, the patients will have to mimic their symptom while wearing an accelerometer (a smartwatch). * second step: both patient groups will be recorded at home through a portative EEG while tagging their symptom through a smartwatch (also used for accelerometry). After the recording, the patients will keep the smartwatch for 2 weeks, still tagging their sympoms (compulsions or tics).
CONDITIONS
Official Title
Objective Characterizatoion of Repetitive Behaviors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be between 15 and 65 years old
- Have Obsessive-Compulsive Disorder and/or Gilles de la Tourette Syndrome (including related depressive, anxious, or ADHD conditions)
- Be registered with French social security or an equivalent
- Provide written consent to participate
- Women must use contraception or not be sexually active
You will not qualify if you...
- Have any psychiatric disorders other than those listed in inclusion criteria
- Have any neurological disorders other than Gilles de la Tourette Syndrome
- Be unable to make decisions for themselves
- Be pregnant
- Have contraindications for MRI
- Not speak French
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Hôpital Albert Chenevier
Créteil, France, 94000
Actively Recruiting
2
Hôpital Henri Mondor
Créteil, France, 94010
Actively Recruiting
3
Hôpital Pitié Salpêtrière
Paris, France, 75013
Actively Recruiting
Research Team
L
Luc MALLET, MD
CONTACT
H
Hugues LAMOTHE, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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