Actively Recruiting
Optical Coherence Tomography And NEphropathy: The OCTANE Study
Led by University of Edinburgh · Updated on 2026-05-13
150
Participants Needed
1
Research Sites
746 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients with high blood pressure (hypertension) and chronic kidney disease are at an increased risk of developing heart disease and strokes. Part of this risk is due to changes in the structure and function of the blood vessels throughout the body. It is thought that reducing high blood pressure and treating chronic kidney disease improves the structure and function of blood vessels but information on this is limited. Optical coherence tomography (OCT) is a method of looking at the blood vessels at the back of the eye. It is a simple, quick and non-invasive test that you may have previously had during a visit to the optician. The purpose of the study is to ascertain whether OCT is able to detect changes in the eye's blood vessels in patients with hypertension and chronic kidney disease compared to healthy individuals and also to see if any differences seen improve with treatment.
CONDITIONS
Official Title
Optical Coherence Tomography And NEphropathy: The OCTANE Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female
- Age 18-80
- Body mass index 435
- For those with hypertension: blood pressure 4140/90 or on treatment for hypertension
- For those with chronic kidney disease: CKD as defined by Kidney Diseases Quality Initiative guidelines
You will not qualify if you...
- Under legal consent age or mentally or legally incapacitated
- Donated 450 ml of blood within the last 4 weeks
- Past or present drug or alcohol abuse, including intravenous drug abuse
- Participated in another clinical trial within the last month
- Considered at high risk for HIV or hepatitis B
- Known eye disease, previous eye surgery, or refractive error greater than +/- 6 dioptres
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Edinburgh
Edinburgh, Midlothian, United Kingdom, EH164TJ
Actively Recruiting
Research Team
N
Neeraj Dhaun, MD PhD
CONTACT
D
David Webb
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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