Study on Effects of Eating Oregano and Basil Leaves to Reduce Inflammation and Improve Lipid Levels in Patients with Unstable Angina

What this Trial Is About

Researchers are investigating the effects of increasing dietary polyphenol intake by consuming oregano and basil leaves on inflammation and lipid levels in patients who have recently experienced unstable angina, a type of acute coronary syndrome. The study is based on evidence that polyphenols, found in many plant foods, may help reduce inflammation and improve heart health by acting as antioxidants and modulating blood lipids. Oregano and basil leaves are rich sources of these compounds, especially rosmarinic acid, which might support cardiovascular protection. The study is a randomized controlled trial lasting two months. Participants are randomly assigned to either a control group receiving standard medical treatment and general dietary advice or to an experimental group who, in addition to standard treatment, consume 4-5 grams each of dried oregano and basil leaves daily. All participants are instructed to avoid other herbal medications or dietary supplements during the study. During the study, participants will have their blood and urine tested for inflammatory biomarkers, plasma lipids, malondialdehyde, and total urinary polyphenols at the start and after two months. Researchers will also measure plasma PCSK9 and PAI-1 levels to assess changes. The study aims to monitor these factors to understand the potential impact of increased polyphenol intake along with standard care in patients with unstable angina.

Oregano and Basil Leaves and Coronary Artery Disease