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ID06890013

Study Evaluating Flow Mediated Dilatation and Cor-IS Technology in Adults Hospitalized with Acute Coronary Syndromes

Led by Aristotle University Of Thessaloniki · Updated on 2026-03-02

100

Participants Needed

1

Research Sites

21 weeks

Total Duration

AI-Summary

What this Trial Is About

Researchers are conducting a prospective, single-center observational study to understand how flow mediated dilatation FMD can predict outcomes in patients with acute coronary syndromes ACS. This study also evaluates the use of a new method called Cor-IS technology alongside echocardiographic and biochemical measurements. The study focuses on patients hospitalized with ACS, including ST-segment elevation myocardial infarction STEMI and non-ST-segment elevation myocardial infarction NSTEMI. Participants will undergo assessments of their endothelial function using two methods traditional flow mediated dilatation of the brachial artery and the novel Cor-IS technology. They will also receive transthoracic echocardiograms and have blood samples taken to measure plasma biomarkers. All evaluations are observational, meaning no treatments are assigned by the study. These procedures aim to monitor heart function and biochemical markers over time. During the study, researchers will track patient outcomes for 12 months, focusing on measures such as brachial artery function, major adverse cardiac events MACE, rehospitalizations for angina, need for revascularization, and heart failure occurrences. Participants must be able to consent and follow the studys schedule. This helps researchers gather comprehensive data on the predictive value of the tested methods in ACS. The total participation covers the initial hospitalization and follow-up assessments during the year after enrollment.

CONDITIONS

Brief Title

A Prospective, Single-center, Observational Study Aiming to Assess the Predictive Role of Flow Mediated Dilatation in Acute Coronary Syndromes, Combined With Echocardiographic and Biochemical Indices

Research Team

C

Christodoulos E. Papadopoulos, PhD

G

Georgios Zormpas, MD

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