Actively Recruiting

Age: 18Years +
All Genders
NCT04678011

A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy

Led by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Updated on 2026-02-23

1000

Participants Needed

2

Research Sites

257 weeks

Total Duration

On this page

Sponsors

A

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Lead Sponsor

L

Leiden University Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to determine the efficacy and safety of a personalised surveillance and intervention protocol for patients with familial adenomatous polyposis (FAP) that have undergone (procto)colectomy.

CONDITIONS

Official Title

A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of familial adenomatous polyposis (FAP) confirmed by genetic testing or clinical diagnosis with more than 100 colorectal adenomas and positive family history
  • Have undergone prophylactic (procto)colectomy with ileorectal, ileosigmoidal anastomosis (IRA/ISA), or ileal pouch-anal anastomosis (IPAA)
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Unable to remove all polyps needing removal during one or more clearing endoscopies
  • Presence of cancer at baseline endoscopy
  • Need for surgery

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

MD Anderson

Houston, Texas, United States, 77030

Actively Recruiting

2

Academic Medical Centre

Amsterdam, North Holland, Netherlands, 1105AZ

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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