Actively Recruiting
Personological Structure, Cognitive Functions and Central Sensitization in Headache: Obstacles and Resources in the Treatment of Chronic and Episodic Headache
Led by IRCCS Centro Neurolesi Bonino Pulejo · Updated on 2025-12-08
64
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the complex nature of headache, both episodic and chronic forms, focusing on neurological, cognitive, and psychological aspects. The study aims to understand differences between these forms and assess how factors like central sensitization, personality traits, and mental health conditions affect pain management and treatment adherence. This observational study seeks to improve therapeutic approaches and enhance quality of life by preventing progression to chronic headache. This study involves two assessment points: an initial baseline visit (T0) and a follow-up about six months later (T1). It enrolls adults aged 18 to 60 with diagnosed chronic or episodic headache attending a specialized clinic. Participants complete a battery of tests at both visits, including cognitive assessments, pain and sensitization scales, personality inventories, treatment adherence questionnaires, psychological distress measures, and surveys on digital habits. Participants provide clinical and demographic information at the start and undergo repeated evaluations to track changes over time. The study monitors cognitive functions, pain intensity, central sensitization, personality, psychological symptoms, treatment engagement, and digital behavior patterns. Data are securely stored, and participants' progress is analyzed over approximately six months, with the entire project lasting about three years from enrollment through data analysis and reporting.
CONDITIONS
Brief Title
PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENSITIZATION IN HEADACHE
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 60 years
- Diagnosis of chronic or episodic headache
- Patients attending the Headache Outpatient Clinic
You will not qualify if you...
- Presence of severe psychiatric and neurological disorders
- Presence of oncological diseases in terminal stage
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo a comprehensive neuropsychological assessment including clinical history, cognitive function tests, pain evaluation, personality assessment, treatment adherence, psychological distress, and digital habits questionnaires.
1 visit (in-person)
Duration - Approximately 6 months after baseline
Approximately six months after baseline, participants return for follow-up to repeat the neuropsychological assessment and evaluate changes over time.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Irccs Centro Neurolesi Bonino Pulejo
Messina, Sicily, Italy, 98066
Actively Recruiting
Research Team
A
Anna Anselmo, Psychologist
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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