Actively Recruiting
Physical Fitness and Hot Executive Function in Alzheimer's Risk
Led by National Taiwan Normal University · Updated on 2025-07-23
240
Participants Needed
1
Research Sites
133 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This 18-month study tracks how physical fitness relates to executive function in older adults, aiming to determine if fitness improvements predict better cognitive performance. Participants complete assessments at baseline and 18 months, including cardiorespiratory fitness (YMCA bike test), muscle strength (chest and leg press tests), and executive function (computer tasks with brain activity recording via EEG). Additional measures include physical activity questionnaires, cognitive screening (MMSE), memory tests (digit span), demographics (age, sex, education), and blood tests for APOE ε4 gene status. No exercise program will be provided, allowing observation of natural fitness-cognition relationships in daily life.
CONDITIONS
Official Title
Physical Fitness and Hot Executive Function in Alzheimer's Risk
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 50-70
- Able to engage in fitness testing
- Normal vision or corrected-to-normal vision
You will not qualify if you...
- Suffering from cardiopulmonary-related diseases
- Suffering from cognitive, neurological or psychiatric disorders (e.g., dementia, Parkinson's disease, epilepsy, depression, schizophrenia, etc.)
- Suffering from infectious diseases (e.g., hepatitis, human immunodeficiency virus or Creutzfeldt-Jakob disease)
- Having a history of drug or alcohol abuse
- Having colour vision deficiency (e.g., colour blindness)
- Having a family history of aneurysm
- Taking medications that affect brain function
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Taiwan Normal University
Taipei, Taiwan
Actively Recruiting
Research Team
C
Chine-Heng Chu, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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