Actively Recruiting
Pilot Study of the Human Metagenome in Metabolic Diseases
Led by Sengkang General Hospital · Updated on 2025-05-15
600
Participants Needed
1
Research Sites
228 weeks
Total Duration
On this page
Sponsors
S
Sengkang General Hospital
Lead Sponsor
S
Singapore General Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a cohort study to understand the role of the human metagenome, and associated metabolites, in health and in various diseased states, in particular obesity as well as sarcopenia. Recruited participants will have their fecal, salivary, urine, serum, and in certain instances, mucosal samples taken, for metagenomic sequencing and metabolite testing. We hope to uncover various differences and signatures in the metagenome and metabolome in various diseased states, with potential future therapeutic applications in personalised medicine.
CONDITIONS
Official Title
Pilot Study of the Human Metagenome in Metabolic Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Obese individuals with BMI greater than 27.5 kg/m2
- Sarcopenic patients with low handgrip strength (<26 kg for males; <18 kg for females) and/or low gait speed (<0.8 m/s) along with low muscle mass (<7.0 kg/m2 for males; <5.7 kg/m2 for females)
- Healthy control subjects without sarcopenia and with BMI less than 27.5 kg/m2
You will not qualify if you...
- No informed consent provided
- Presence of intestinal stoma preventing fecal sample collection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sengkang General Hospital
Singapore, Singapore, 544886
Actively Recruiting
Research Team
K
Koy Min Chue
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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