Predictors for Survival and Good Neurological Outcome in E-CPR and Non CPR Treated Patients

What this Trial Is About

Researchers are studying patients who receive extracorporeal cardiopulmonary resuscitation (ECPR) during cardiac arrest or extracorporeal membrane oxygenation (ECMO) treatment without cardiac arrest. The study aims to improve patient selection for ECPR by developing and validating a tool to predict good neurological outcomes. It also evaluates the sterility and function of pre-primed ECMO circuits, tests the accuracy of neurological prognostication guidelines for ECPR patients, and assesses survivors' long-term neuropsychological outcomes and life satisfaction up to 12 years after treatment. The study includes patients treated with ECMO during cardiac arrest and those treated with ECMO for circulatory failure without cardiac arrest as a comparison group. No interventions are performed as part of the study; instead, researchers observe and compare outcomes between these groups. The study monitors ECMO oxygenator function, cultures the pre-primed ECMO circuits to check for infection, and applies neurological tests to assess prognosis after cardiac arrest. Participants undergo long-term follow-up visits with validated questionnaires and neuropsychological testing for up to 12 years. These assessments evaluate life satisfaction, anxiety, depression, fatigue, cognitive function, and physical activity. Researchers also measure outcomes such as the Modified Rankin Scale after one year, performance of ECMO oxygenators, culture results from ECMO circuits, and the predictive value of neurological guidelines. The study collects detailed data to better understand the challenges faced by survivors and improve future care.

Predictors for Survival and Good Neurological Outcome in E-CPR and Non CPR Treated Patients