Effects of comprehensive lifestyle modification on blood pressure control: main results of the PREMIER clinical trial.
Lawrence J Appel, Catherine M Champagne, David W Harsha...
https://pubmed.ncbi.nlm.nih.gov/12709466Completed
Phase 3
Age: 25Years - 100Years
All Genders
ID00000616
Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2016-02-18
N/A
Participants Needed
N/A
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
To compare the effectiveness of advice versus two multicomponent lifestyle interventions to control blood pressure in participants with Stage 1 hypertension or higher than optimal blood pressure.
CONDITIONS
Official Title
PREMIER: Lifestyle Interventions for Blood Pressure Control
Who Can Participate
Age: 25Years - 100Years
All Genders
Eligibility Criteria
You may qualify if you...
Men and women, age 25 and older who were generally healthy except for higher than optimal or mildly elevated blood pressure.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Site Locations not provided
Location information for this trial is currently unavailable.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
N/A
Allocation
RANDOMIZED
Model
N/A
Primary Purpose
PREVENTION
Number of Arms
0
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Published Research Related To This Trial
Lifestyle modification and blood pressure control: is the glass half full or half empty?
Thomas G Pickering
https://pubmed.ncbi.nlm.nih.gov/12709472Premier: a clinical trial of comprehensive lifestyle modification for blood pressure control: rationale, design and baseline characteristics.
Laura P Svetkey, David W Harsha, William M Vollmer...
https://pubmed.ncbi.nlm.nih.gov/12875806Comprehensive lifestyle modification and blood pressure control: a review of the PREMIER trial.
Heather L McGuire, Laura P Svetkey, David W Harsha...
https://pubmed.ncbi.nlm.nih.gov/15249794Effect of lifestyle modifications on blood pressure by race, sex, hypertension status, and age.
L P Svetkey, T P Erlinger, W M Vollmer...
https://pubmed.ncbi.nlm.nih.gov/15385946Physical activity, cardiorespiratory fitness, and their relationship to cardiovascular risk factors in African Americans and non-African Americans with above-optimal blood pressure.
Deborah R Young, Mikel Aickin, Phillip Brantley...
https://pubmed.ncbi.nlm.nih.gov/15810564Informing cancer prevention strategies for African Americans: the relationship of African American acculturation to fruit, vegetable, and fat intake.
Jamy D Ard, Celette Sugg Skinner, Chuhe Chen...
https://pubmed.ncbi.nlm.nih.gov/16015458Perceptions of African-American culture and implications for clinical trial design.
Jamy D Ard, Raegan W Durant, Lori Carter Edwards...
https://pubmed.ncbi.nlm.nih.gov/15825976Effects of comprehensive lifestyle modification on diet, weight, physical fitness, and blood pressure control: 18-month results of a randomized trial.
Patricia J Elmer, Eva Obarzanek, William M Vollmer...
https://pubmed.ncbi.nlm.nih.gov/16585662Impact of comprehensive lifestyle interventions on plasma branched-chain amino acid concentrations: a randomized trial.
Yu Jin Lim, Rob M van Dam
https://pubmed.ncbi.nlm.nih.gov/41106729