Actively Recruiting
Preoperative Evaluation of IVC Collapsibility Index and Caval Aorta Index for Prediction of Hypotension After Induction of General Anesthesia in Patients Undergoing Craniotomy Surgeries
Led by Ain Shams University · Updated on 2026-02-10
36
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
Researchers are evaluating the accuracy and consistency of two ultrasound measurements—the Inferior Vena Cava (IVC) collapsibility index and the caval aorta index—to predict low blood pressure (hypotension) after the start of general anesthesia. This study focuses on patients undergoing elective brain surgery (craniotomy) and aims to improve understanding of how preoperative volume status affects blood pressure changes during anesthesia induction. The study involves measuring the IVC collapsibility index, which calculates changes in the IVC diameter during breathing, and the caval aorta index, which compares the size of the IVC to the abdominal aorta. These ultrasound assessments are performed before anesthesia induction, and patients scheduled for elective craniotomy surgeries are observed during and after anesthesia to monitor blood pressure changes. Participants will have their ultrasound measurements taken before anesthesia and will be monitored for blood pressure changes up to 15 minutes after anesthesia induction. Researchers will evaluate the sensitivity and specificity of these ultrasound indexes to predict hypotension. The study includes assessments of patient physical status, fasting status, and other clinical factors related to anesthesia. The total participation involves preoperative evaluation and monitoring during the induction period.
CONDITIONS
Brief Title
Preoperative Evaluation of IVC Collapsibility Index and Caval Aorta Index After Induction of General Anesthesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age from 18 to 40 years
- Both sexes
- Body Mass Index less than 40 kg/m²
- American Society of Anesthesiologists (ASA) physical status I or II
- Fasted according to ASA guidelines: 2 hours for clear fluids, 6 hours after light meal, 8 hours after full high-calorie or fat meal
- Scheduled for elective craniotomy surgery before induction of general anesthesia
You will not qualify if you...
- Current or recent pregnancy within 3 months
- Pre-existing cardiac disease or hypertension
- Taking medications that affect blood pressure such as beta-blockers or calcium channel blockers
- Refusal to undergo the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo ultrasound measurements of the inferior vena cava collapsibility index and caval aorta index before induction of general anesthesia.
1 visit (in-person, preoperative)
Duration - 15 minutes post-induction
Participants are monitored for blood pressure changes 15 minutes after induction of general anesthesia to evaluate sensitivity and specificity of ultrasound indices.
Continuous monitoring during surgery preparation
Trial Site Locations
Total: 1 location
1
Ain Shams University Hospitals
Cairo, Egypt, 11591
Actively Recruiting
Research Team
V
Verina F Zaref, MSc
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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