Adipose Tissue Insulin Resistance Is Not Associated With Changes in the Degree of Obesity in Children and Adolescents.
Rana Halloun, Alfonso Galderisi, Sonia Caprio...
https://pubmed.ncbi.nlm.nih.gov/36469736Status Unknown
Age: 8Years - 18Years
All Genders
Healthy Volunteers
ID00000112
Prevalence of Carbohydrate Intolerance in Lean and Obese Children
Led by National Center for Research Resources (NCRR) · Updated on 2005-06-24
N/A
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
The prevalence of obesity in children is reaching epidemic proportions. Excess adiposity is more than just a cosmetic problem, having substantial metabolic consequences. Insulin resistance, hyperinsulinemia, impaired glucose tolerance, and frank diabetes are often seen in obese children. In this study the prevalence of impaired glucose (carbohydrate) tolerance in lean children with a family history of diabetes and obese children with acanthosis nigricans with or without a family history of diabetes mellitus will be studied.
CONDITIONS
Brief Title
Prevalence of Carbohydrate Intolerance in Lean and Obese Children
Who Can Participate
Age: 8Years - 18Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
Inclusion Criteria:
- Obesity: BM +/- 95% for age general good health
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 1 location
1
Yale University School of Medicine, Pediatric Endocrinology
New Haven, Connecticut, United States, 06520-8064
Actively Recruiting
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Research Team
S
Sonia Caprio, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
Lack of Evidence for a Causal Role of Hyperinsulinemia in the Progression of Obesity in Children and Adolescents: A Longitudinal Study.
Rana Halloun, Alfonso Galderisi, Sonia Caprio...
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