Actively Recruiting

Phase 3
Age: 75Years +
All Genders
ID05366075

The Preventing Functional Decline in Acutely Hospitalized Older Patients (PREV_FUNC) Study Comparing Exercise Programs and Usual Care

Led by Karolinska Institutet · Updated on 2024-12-20

320

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

Sponsors

K

Karolinska Institutet

Lead Sponsor

S

Swedish Council for Working Life and Social Research

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are investigating how different types of exercise programs impact physical function in older adults hospitalized in geriatric medical wards. This study compares a comprehensive multicomponent exercise program, a simpler program with basic exercises, and usual care to see their effects on physical function, daily activities, quality of life, muscle loss, falls, readmissions, and mortality. Participants are aged 75 years and older, and assessments occur at admission, discharge, and three months post-discharge. The trial includes three groups: one group follows a simple exercise program with up to four daily sessions involving sit-to-stand exercises and walking; another group participates in a comprehensive program with two daily supervised sessions focusing on resistance, balance, gait, and functional exercises; and a control group receives usual care, which may include rehabilitation if needed. Exercises are performed on weekdays during the hospital stay, lasting about one week, with encouragement to continue post-discharge. Participants undergo evaluations at hospital admission, discharge, and three months after leaving the hospital. These include tests of physical function, daily living activities, health-related quality of life, sarcopenia (muscle loss), and recording of falls. Researchers also track hospital readmissions and mortality for up to one year after discharge. The study uses double-blind randomization to assign participants, aiming to provide detailed data on how exercise interventions can prevent functional decline in older hospitalized adults.

CONDITIONS

Brief Title

The Preventing Functional Decline in Acutely Hospitalized Older Patients (PREV_FUNC) Study

Who Can Participate

Age: 75Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to stand up from a sitting position independently or with minimal personal help
  • Ability to communicate and collaborate with the research staff
  • Aged 75 years or older
  • Hospitalized in geriatric medical wards
Not Eligible

You will not qualify if you...

  • Inability to follow instructions
  • Assessed by a physician as not eligible due to terminal illness or major medical condition contraindicating exercise
  • Living in a nursing home
  • Previously included in the study
  • Unable to communicate or cooperate with study staff effectively (implied from exclusion criteria and inclusion requirements)

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Approximately 1 week

Participants receive either a simple or comprehensive exercise program during their hospital stay, or usual care. Exercises are performed on weekdays from hospital admission until discharge, around 1 week. After discharge, those in the exercise groups are encouraged to continue at home.

Daily sessions on weekdays during hospital stay

Follow-up

Duration - Up to 1 year after hospital discharge

Participants are assessed at discharge and again 3 months after discharge for physical function, activities of daily living, quality of life, sarcopenia, and falls. Mortality and readmissions are monitored up to 1 year after discharge.

3 visits: at discharge, 3 months post-discharge, and periodic monitoring up to 1 year

Trial Site Locations

Total: 1 location

1

Anna-Karin Welmer

Huddinge, Sweden, 141 83

Actively Recruiting

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Research Team

A

Anna-Karin Welmer, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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Published Research Related To This Trial

Feasibility of the "Preventing functional decline in acutely hospitalized older patients (PREV_FUNC)" study-A three-armed randomized controlled pilot trial.

Linda Sandberg, Anne-Marie Boström, Maria Hagströmer...

https://pubmed.ncbi.nlm.nih.gov/38905174

Study protocol for the 'preventing functional decline in acutely hospitalised older patients (PREV_FUNC)' study: effects of two multicomponent exercise programmes on physical function - a three-armed randomised controlled trial.

Anna-Karin Welmer, Linda Sandberg, Christina Sandlund...

https://pubmed.ncbi.nlm.nih.gov/37607787