Actively Recruiting

Age: 18Years +
All Genders
ID06414928

In-hospital and 30-day Prognostication of Acute Heart Failure Patients by Comparing Four Validated Scores in Emergency Department Patients at a Cardiac Hospital

Led by National Institute of Cardiovascular Diseases, Pakistan · Updated on 2024-05-16

1000

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to determine the prognosis of acute heart failure in patients by comparing four validated risk scores to see which provides better prediction accuracy. It focuses on patients presenting with acute heart failure at a cardiac emergency department and evaluates these scoring systems to improve understanding of patient outcomes over time. Patients who meet eligibility will provide informed consent to use their anonymized data. They will undergo detailed interviews covering demographics and risk factors, and complete validated questionnaires including ADHERE, GWTG-HF Risk Score, OHFRS, and EHMRG30-ST. Participants will be followed for 30 days after hospital admission to record survival status. A sample size of 939 patients has been planned for robust analysis. During the study, data will be verified by cross-checking 10% of records with patient files. Researchers will monitor in-hospital prognosis from admission until discharge or death, and 30-day prognosis from admission up to 30 days. The study involves thorough data collection and follow-up to assess and compare the predictive power of the heart failure risk scores over these periods.

CONDITIONS

Brief Title

Prognostic Model Heart Failure

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older
  • Any gender
  • Patients who visited the emergency department at NICVD, Karachi
  • Newly or previously diagnosed with heart failure
  • Able to provide informed consent
  • Able to be followed up for 30 days via telephone or outpatient clinic
Not Eligible

You will not qualify if you...

  • Patients younger than 18 years
  • Patients who do not give consent
  • Patients with mental handicap due to neurological or psychiatric illness (excluding depression or anxiety)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - From admission until discharge or death

Participants undergo interviews and complete questionnaires including patient demographics and risk factors to assess heart failure severity using validated scoring systems.

1 in-hospital period of observation

Long-term Monitoring

Duration - 30 days from admission

Participants are followed up to assess survival status and prognosis 30 days after hospital admission.

1 follow-up visit or telephone call

Trial Site Locations

Total: 1 location

1

National Institute of Cardiovascular Diseases

Karachi, Sindh, Pakistan, 75510

Actively Recruiting

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Research Team

M

Madiha Fatima, MBBS, FCPS

R

Rajesh Kumar, MBBS, FCPS

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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