Actively Recruiting

Age: 3Years - 18Years
All Genders
ID06201494

Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents

Led by Charles University, Czech Republic · Updated on 2024-06-18

80

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research focuses on bronchial asthma in children and adolescents aged 3 to 18 years, particularly examining both typical symptoms like cough, chest tightness, shortness of breath, and wheezing, and less common symptoms such as chronic productive cough, inspiratory dyspnoea, or recurrent pneumonia. It aims to understand the prevalence of these typical and atypical asthma symptoms and evaluate the sensitivity of the official asthma symptom questionnaire ISAAC in identifying asthma in children presenting with varying symptoms. The study is observational and involves children presenting for their first evaluation in a pulmonary outpatient clinic with respiratory symptoms such as cough, shortness of breath, chest tightness, wheezing, recurrent lung infections, or abnormal lung sounds. The investigators will document asthma symptoms using the ISAAC questionnaire and clinical assessment. Initial suspicion of asthma diagnosis will lead to therapy initiation, followed by a scheduled follow-up within three months to confirm the diagnosis. Participants will undergo an initial checkup with asthma symptom documentation and complete the ISAAC questionnaire. Investigators will monitor the prevalence of typical and atypical asthma symptoms over time and confirm asthma diagnosis through follow-up assessments. The study includes documentation of respiratory symptoms and clinical findings with the aim of improving understanding of asthma presentation in children. The total study duration extends to June 2026.

CONDITIONS

Brief Title

Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents

Who Can Participate

Age: 3Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Child aged 3 to 18 years
  • First evaluation in pulmonary outpatient clinic for respiratory symptoms such as cough, shortness of breath, chest tightness, wheezing, recurrent lower respiratory tract and lung infections, dyspnoea, or abnormal lung sounds
Not Eligible

You will not qualify if you...

  • Presence of other documented chronic respiratory, cardiovascular, neurological, genetic, infectious, or metabolic diseases
  • Significant immaturity or other diseases that may cause respiratory symptoms

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 3 months

Participants undergo initial checkup with asthma symptom documentation and complete the ISAAC questionnaire to assess typical and atypical asthma symptoms.

1 initial visit and 1 follow-up visit within 3 months

Long-term Monitoring

Duration - Ongoing as determined by healthcare providers

Participants with suspected asthma receive observation to confirm diagnosis and evaluate symptom progression over time.

Additional visits depending on clinical needs

Trial Site Locations

Total: 1 location

1

First faculty of Medicine, Charles university.

Prague, Czechia, 128 00

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Research Team

J

Jana Tukova

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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